Jin Tianyu, Chi Li, Ma Chongyang
Class 1, Grade 2018 "5+3" Year Program Clinical Medicine, School of Basic Medicine, Capital Medical University, Youanmenwai, Xitoutiao, Fengtai District, Beijing 100069, China.
School of Traditional Chinese Medicine, Capital Medical University, Youanmenwai, Xitoutiao, Fengtai District, Beijing 100069, China.
Evid Based Complement Alternat Med. 2022 Apr 29;2022:3742208. doi: 10.1155/2022/3742208. eCollection 2022.
Ledeb., which belongs to Agrimonia and Rosaceae, is used in traditional Chinese medicine. It exhibits excellent medicinal properties and has been used to treat various diseases, such as tumors, trichomoniasis, vaginitis, diarrhea, and dysentery. Phytochemical studies have revealed that has over 100 secondary metabolites that can be categorized into six classes, i.e., flavonoids, isocoumarins, triterpenes, phloroglucinol derivatives, tannins, and organic acids. This review summarizes recently published literature on the chemical structures of 90 bioactive compounds that have been identified in and examines their pharmacological properties, including their antitumor, anti-inflammatory, antioxidant, antibacterial, and antidiabetic properties, as well as the potential development of parasitic resistance to these chemicals. This review highlights existing knowledge gap and serves as a basis for developing novel preparations of with medicinal value.
龙牙草属蔷薇科龙牙草属植物,在传统中药中有所应用。它具有出色的药用特性,已被用于治疗多种疾病,如肿瘤、滴虫病、阴道炎、腹泻和痢疾。植物化学研究表明,它含有100多种次生代谢产物,可分为六类,即黄酮类、异香豆素类、三萜类、间苯三酚衍生物、单宁和有机酸。本综述总结了最近发表的关于龙牙草中已鉴定出的90种生物活性化合物化学结构的文献,并研究了它们的药理特性,包括抗肿瘤、抗炎、抗氧化、抗菌和抗糖尿病特性,以及对这些化学物质产生寄生虫抗性的潜在发展情况。本综述突出了现有知识差距,并为开发具有药用价值的龙牙草新制剂提供了依据。