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慢性难愈性溃疡负压封闭引流敷料与生理盐水敷料的对比研究

A Comparative Study Between Vacuum Dressing and Normal Saline Dressing for Chronic Non-Healing Ulcers.

作者信息

M Pragadheeswaran, P Sankar Lingam, Balan Yuvaraj, Pyati Anand K

机构信息

General Surgery, Mundiyampakkam Medical College and Hospital, Villupuram, Tamil Nadu, IND.

General Surgery, Chengalpattu Medical College and Hospital, Chengalpattu, Tamil Nadu, IND.

出版信息

Cureus. 2022 Apr 6;14(4):e23870. doi: 10.7759/cureus.23870. eCollection 2022 Apr.

Abstract

Introduction Isn't it a boon that all living organisms possess the ability to heal their injuries? The wound healing is faster when the normal physiology of the wound healing is maintained. Our understanding of wound healing has undergone dramatic changes in the recent past. Almost all materials and methods available on earth have been used and tested to facilitate the process of wound healing. The mental agony and the disability suffered by patients with chronic ulcers have led to the reappraisal of the basic components of the wound healing process and how they are influenced by biological, mechanical, and physical forces. The Department of General Surgery in our Government Chengalpattu Medical College and Hospital, Chengalpattu, Tamil Nadu, India, admits and treats a large volume of patients with wounds and ulcers. Here many materials are being used regularly for dressing to make wound healing faster. Vacuum dressings were also done on many patients, and promising results were observed. This kindled our interest in conducting this prospective study and comparing wound healing with vacuum dressing versus normal saline dressing. Materials and methods A total of 74 patients were included in the study, out of which 37 patients were randomly included in the experimental group and vacuum dressing was done, while the other 37 included in the control group were treated with dressing done with normal saline moistened gauze and bandage roll. Rates at which the wound healed were compared. Results We were able to observe a statistically significant difference in the rate of appearance of granulation tissue between the two and increased clearance of bacteria and toxins. The study group promised better progress as compared to the control group in various aspects. Conclusion Vacuum dressing brings an obvious improvement in the healing of non-healing ulcers and decreases the overall duration of stay in the hospital.

摘要

引言

所有生物都具备治愈自身损伤的能力,这难道不是一件幸事吗?当伤口愈合的正常生理过程得以维持时,伤口愈合会更快。在最近一段时间里,我们对伤口愈合的理解发生了巨大变化。地球上几乎所有可用的材料和方法都已被使用和测试,以促进伤口愈合过程。慢性溃疡患者所遭受的精神痛苦和残疾状况,促使人们重新审视伤口愈合过程的基本组成部分,以及它们是如何受到生物、机械和物理力量影响的。印度泰米尔纳德邦钦加尔帕图政府钦加尔帕图医学院和医院的普通外科接收并治疗大量伤口和溃疡患者。在这里,许多材料被定期用于包扎,以使伤口愈合更快。许多患者还接受了负压伤口治疗,并且观察到了有前景的结果。这激发了我们开展这项前瞻性研究并比较负压伤口治疗敷料与生理盐水敷料对伤口愈合影响的兴趣。

材料与方法

本研究共纳入74例患者,其中37例患者被随机纳入实验组并进行负压伤口治疗敷料包扎,而另一组37例患者作为对照组,采用生理盐水湿润纱布和绷带卷进行包扎。比较两组伤口愈合的速度。

结果

我们观察到两组之间肉芽组织出现率存在统计学显著差异,并且细菌和毒素清除增加。与对照组相比,研究组在各个方面都显示出更好的进展。

结论

负压伤口治疗敷料在难愈合溃疡的愈合方面带来了明显改善,并缩短了患者的总体住院时间。

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