Santosa Yudistira, Harca Azizah Dhena, Sukmaja Edwin, Yuwono Angelina
Department of Internal Medicine, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, IDN.
General Medicine, Primaya Hospital, Jakarta, IDN.
Cureus. 2022 Apr 5;14(4):e23857. doi: 10.7759/cureus.23857. eCollection 2022 Apr.
Type 2 diabetes mellitus is a major risk factor for all forms of cardiovascular diseases, including peripheral arterial disease (PAD). Chronic limb-threatening ischemia (CLTI) is determined by the presence of ischemic rest pain, and may or may not be accompanied by tissue loss (such as ulcers and gangrene) or infection. Treatments for CLTI consist of wound treatment, infection control, and ischemia control by arterial revascularization, which can be performed by either open surgical procedure (bypass) or an endovascular approach. We present two cases of chronic limb-threatening ischemia, one with an above-knee lesion and the other with a below-knee lesion. In addition to good wound treatment and glucose control as the risk factor management, we performed endovascular therapy in both patients. Both patients showed good wound improvement after the procedure.
2型糖尿病是包括外周动脉疾病（PAD）在内的所有形式心血管疾病的主要危险因素。慢性肢体威胁性缺血（CLTI）由缺血性静息痛确定，可能伴有或不伴有组织缺失（如溃疡和坏疽）或感染。CLTI的治疗包括伤口处理、感染控制以及通过动脉血运重建控制缺血，动脉血运重建可通过开放手术（搭桥）或血管内介入方法进行。我们展示了两例慢性肢体威胁性缺血病例，一例为膝上病变，另一例为膝下病变。除了作为危险因素管理的良好伤口处理和血糖控制外，我们对两名患者均进行了血管内治疗。术后两名患者的伤口均有明显改善。
