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牙齿漂白后牙髓血氧饱和度读数的评估:一项随机临床试验。

Evaluation of the Pulp Oxygen Saturation Reading after Tooth Bleaching: A Randomized Clinical Trial.

作者信息

Neves Henriques Dilma Helena, Alves Ana Maria Hecke, Pottmaier Larissa Fernanda, Garcia Lucas da Fonseca Roberti, Bortoluzzi Eduardo Antunes, Teixeira Cleonice Silveira

机构信息

Department of Dentistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.

Department of Dentistry, ABCD Magic School, Florianópolis, Santa Catarina, Brazil.

出版信息

Int J Dent. 2022 Apr 28;2022:1598145. doi: 10.1155/2022/1598145. eCollection 2022.

DOI:10.1155/2022/1598145
PMID:35531572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9072050/
Abstract

OBJECTIVES

The purpose of this clinical trial was to evaluate the influence of in-office dental bleaching on the pulp oxygen saturation (SpOp) reading. . SpOp was measured using a pulse oximeter in 112 upper and lower anterior teeth (canines and incisors) of patients submitted to bleaching. Whitegold Office 35% (WGO) (upper and lower left hemiarch) and Whiteness HP Auto Mixx 35% (WHP) (upper and lower right hemiarch) bleaching agents were used. SpO measurements (teeth and index finger) were taken before and after each of the three application sessions of the agents. In the 4 session, in which no bleaching gel was used, only SpO was measured. Before and after the bleaching sessions, a colorimetric device performed the teeth color reading. The waiting time between sessions was 7 days. Data were analyzed by the Friedman, Kruskal-Wallis, and Mann-Whitney tests ( = 0.05). Color change (Δ) data were correlated (Spearman's Rho test) with the SpOp levels.

RESULTS

Neither of the two bleaching agents showed significant differences between the readings when evaluated individually (WGO, =0.780, and WHP, =0.494). When taken together, the results showed significant difference between the readings performed, with higher median values after bleaching sessions: before (97.3) and after (98.6) 1 session; before (98.3) and after (98.3) 2 session; before (98.3) and after (99.0) 3 session; and after 1 week (98.3). The dental groups formed by maxillary lateral incisors (=0.012) and mandibular incisors ( < 0.001) showed a significant difference. Spearman's Rho test showed a nonsignificant and weak correlation between Δ and SpOp in most comparisons.

CONCLUSIONS

The in-office dental bleaching influenced the SpOp reading, regardless of the dental group evaluated or the bleaching agent used. . This study provides information about the influence of in-office tooth whitening on the pulp SpOp levels. The observation of pulp vitality during and after the use of bleaching agents is important for the follow-up of patients undergoing tooth whitening. The use of a pulse oximeter may be a viable and painless alternative to perform this monitoring. The clinical trial was registered with the Brazilian Registry of Clinical Trials (ReBEC; registration number: https://clinicaltrials.gov/ct2/show/RBR-68xbth).

摘要

目的

本临床试验旨在评估诊室牙齿漂白对牙髓血氧饱和度(SpOp)读数的影响。对112颗接受漂白治疗患者的上下前牙(尖牙和切牙)使用脉搏血氧仪测量SpOp。使用Whitegold Office 35%(WGO)(上下左半牙弓)和Whiteness HP Auto Mixx 35%(WHP)(上下右半牙弓)漂白剂。在每次使用漂白剂的三个疗程前后测量SpO(牙齿和食指)。在第4个疗程中,未使用漂白凝胶,仅测量SpO。在漂白疗程前后,用比色仪进行牙齿颜色读数。各疗程之间的等待时间为7天。数据采用Friedman检验、Kruskal-Wallis检验和Mann-Whitney检验进行分析(α = 0.05)。颜色变化(Δ)数据与SpOp水平进行相关性分析(Spearman秩相关检验)。

结果

单独评估时,两种漂白剂的读数之间均未显示出显著差异(WGO,P = 0.780;WHP,P = 0.494)。综合来看,结果显示测量读数之间存在显著差异,漂白疗程后中位数更高:第1个疗程前(97.3)和后(98.6);第2个疗程前(98.3)和后(98.3);第3个疗程前(98.3)和后(99.0);以及1周后(98.3)。由上颌侧切牙(P = 0.012)和下颌切牙(P < 0.001)组成的牙齿组显示出显著差异。Spearman秩相关检验显示,在大多数比较中,Δ与SpOp之间的相关性不显著且较弱。

结论

无论评估的牙齿组或使用的漂白剂如何,诊室牙齿漂白都会影响SpOp读数。本研究提供了关于诊室牙齿美白对牙髓SpOp水平影响的信息。在使用漂白剂期间及之后观察牙髓活力对于接受牙齿美白治疗的患者的随访很重要。使用脉搏血氧仪可能是进行这种监测的一种可行且无痛的替代方法。该临床试验已在巴西临床试验注册中心(ReBEC;注册号:https://clinicaltrials.gov/ct2/show/RBR-68xbth)注册。

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J Appl Oral Sci. 2019;27:e20180442. doi: 10.1590/1678-7757-2018-0442. Epub 2019 Apr 11.
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Effect of Calcium and Fluoride Addition to Hydrogen Peroxide Bleaching Gel On Tooth Diffusion, Color, and Microhardness.钙离子和氟化物添加剂对过氧化物漂白凝胶作用于牙齿的扩散、颜色和显微硬度的影响。
Oper Dent. 2019 Jul/Aug;44(4):424-432. doi: 10.2341/18-113-L. Epub 2019 Jan 23.
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In Vivo Evaluation of Customized Pulse Oximeter and Sensitivity Pulp Tests for Assessment Of Pulp Vitality.
定制脉搏血氧仪和敏感性牙髓测试用于评估牙髓活力的体内评估
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Effect of At-Home Bleaching on Oxygen Saturation Levels in the Dental Pulp of Maxillary Central Incisors.家庭漂白对上颌中切牙牙髓氧饱和度水平的影响。
Braz Dent J. 2018 Nov-Dec;29(6):541-546. doi: 10.1590/0103-6440201802170.
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In-office tooth bleaching with 38% hydrogen peroxide promotes moderate/severe pulp inflammation and production of ll-1β, TNF-β, GPX, FGF-2 and osteocalcin in rats.使用38%过氧化氢进行诊室牙齿漂白会引发大鼠中度/重度牙髓炎症,并促进白细胞介素-1β、肿瘤坏死因子-β、谷胱甘肽过氧化物酶、成纤维细胞生长因子-2和骨钙素的产生。
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