National Centre for Immunisation Research and Surveillance, Sydney Children's Hospitals Network, Sydney, Australia.
School of Population Health, University of New South Wales, Sydney, Australia.
J Infect Dis. 2022 Nov 28;226(11):1882-1886. doi: 10.1093/infdis/jiac184.
We estimated attack rates of severe acute respiratory syndrome coronavirus 2 Omicron (B.1.1.529) infection among people attending a nightclub and a graduation ball where >95% had at least 2 vaccine doses. Attack rates were 295 of 535 (55.1%) and 102 of 189 (54.0%), respectively (mean, 5 days postevent). At the ball, attack rates increased with time since vaccination: 12.5% among those vaccinated 1-2 months previously and 68.0% among those vaccinated ≥3 months previously; such differences were not found at the nightclub. Recent vaccination prevents Omicron infection, but is time and setting dependent, emphasizing the importance of nonpharmaceutical public health measures in addition to vaccine booster doses to maximize protection in high-risk contexts.
我们估计了在一家夜总会和一个毕业典礼舞会中，感染严重急性呼吸综合征冠状病毒 2 型奥密克戎（B.1.1.529）的攻击率。这两个地方的人群中，超过 95%的人至少接种了两剂疫苗。分别有 295 人（55.1%）和 102 人（54.0%）（平均在事件发生后 5 天）在夜总会和毕业典礼舞会中受到感染。在毕业典礼舞会上，随着接种疫苗后时间的推移，感染率增加：接种疫苗 1-2 个月的人感染率为 12.5%，而接种疫苗≥3 个月的人感染率为 68.0%；在夜总会中未发现此类差异。最近的疫苗接种可以预防奥密克戎感染，但与时间和环境有关，这强调了在高风险环境中，除了疫苗加强针之外，还需要采取非药物公共卫生措施来最大程度地保护人们。
