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细菌如何克服植物中鞭毛蛋白的模式识别。

How bacteria overcome flagellin pattern recognition in plants.

机构信息

Department of Plant Sciences, University of Oxford, South Parks Road, Oxford, OX1 3RB, UK.

Department of Plant Sciences, University of Oxford, South Parks Road, Oxford, OX1 3RB, UK.

出版信息

Curr Opin Plant Biol. 2022 Jun;67:102224. doi: 10.1016/j.pbi.2022.102224. Epub 2022 May 6.

Abstract

Efficient plant immune responses depend on the ability to recognise an invading microbe. The 22-amino acids in the N-terminal domain and the 28-amino acids in the central region of the bacterial flagellin, called flg22 and flgII-28, respectively, are important elicitors of plant immunity. Plant immunity is activated after flg22 or flgII-28 recognition by the plant transmembrane receptors FLS2 or FLS3, respectively. There is strong selective pressure on many plant pathogenic and endophytic bacteria to overcome flagellin-triggered immunity. Here we provide an overview of recent developments in our understanding of the evasion and suppression of flagellin pattern recognition by plant-associated bacteria.

摘要

有效的植物免疫反应依赖于识别入侵微生物的能力。细菌鞭毛蛋白的 N 端结构域中的 22 个氨基酸和中央区域的 28 个氨基酸,分别称为 flg22 和 flgII-28,是植物免疫的重要激发子。flg22 或 flgII-28 被植物跨膜受体 FLS2 或 FLS3 识别后,植物免疫被激活。许多植物病原和内生细菌都面临着强烈的选择性压力,需要克服鞭毛蛋白触发的免疫。本文概述了我们对植物相关细菌逃避和抑制鞭毛蛋白模式识别的最新理解。

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