喉炎性肌纤维母细胞瘤：一例报告
Inflammatory myofibroblastic tumour of the larynx: report of a case.
作者信息
Colizza Andrea, Meliante Piero Giuseppe, Donsante Samantha, Riminucci Mara, Greco Antonio, De Vincentiis Marco, Corsi Alessandro
机构信息
Department of Sense Organs, Sapienza University of Rome, Italy.
Department of Molecular Medicine, Sapienza University of Rome, Italy.
出版信息
Ear Nose Throat J. 2025 Feb;104(2):NP68-NP71. doi: 10.1177/01455613221101087. Epub 2022 May 9.
Only 0.3-1% of laryngeal cancer are non-squamous cell neoplasms. Of these, a rare entity is inflammatory myofibroblastic tumour (IMT), in which anaplastic lymphoma kinase-1 (ALK-1) is frequently expressed. Just 50 cases of IMT have been reported. Therefore, many otolaryngologists may be unfamiliar with this type of tumour and be prone to its over- or undertreatment.We report a case of ALK-1-negative IMT treated with transoral endoscopic excision and disease-free 6 months after surgery.
仅0.3%-1%的喉癌是非鳞状细胞肿瘤。其中，一种罕见的实体是炎性肌纤维母细胞瘤（IMT），间变性淋巴瘤激酶-1（ALK-1）在该肿瘤中经常表达。仅报告了50例IMT病例。因此，许多耳鼻喉科医生可能不熟悉这种类型的肿瘤，容易对其过度治疗或治疗不足。我们报告1例经口内镜切除治疗的ALK-1阴性IMT病例，术后6个月无疾病复发。
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