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异体骨移植治疗胫骨平台骨折的影像学和临床结果。

Radiographic and clinical outcome of tibial plateau fractures treated with bone allograft.

机构信息

Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

Dept. of Orthopaedics and Traumatology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

出版信息

Arch Orthop Trauma Surg. 2023 May;143(5):2447-2454. doi: 10.1007/s00402-022-04461-x. Epub 2022 May 10.

Abstract

BACKGROUND

To determine the clinical outcome of patients who had been treated with bone allografts during open reduction and internal fixation (ORIF) of tibial head fractures.

METHODS

Patients who suffered a medial, lateral, or bicondylar fracture of the tibial plateau and underwent surgical treatment by open reduction and internal fixation (ORIF) using human femoral head bone allografts were included. Patients were invited to provide information for the following: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), EuroQol Five Dimension score (EQ-5D), Lower Extremity Functional Scale (LEFS) and Parker Mobility Score. Bone mineral density (BMD) of the allograft area and the healthy human bone tissue were measured by quantitative computed tomography.

RESULTS

A total of 22 patients with a mean follow-up time of 2.88 ± 2.46 years were included in our study. The most common fractures observed in this study were classified as Schatzker II (11 patients, 50.0%) or AO/OTA 41.B3 (12 patients, 54.5%) fractures. Postoperative WOMAC total was 13.0 (IQR = 16.3, range 0-33). Median quality of life (EQ-5D) score was 0.887 ± 0.121 (range 0.361-1.000). Median Lower Extremity Functional Scale (LEFS) score was 57.5 ± 19.0 (range 33-79). Mean Parker Mobility Score was 9 (range 6-9). Median bone mineral density (BMD) for the whole group was 300.04 ± 226.02 mg/cm (range - 88.68 to 555.06 mg/cm) for region of interest (ROI 5) (central), 214.80 ± 167.45 mg/cm (range - 7.16 to 597.21 mg/cm) for ROI 1-4 (marginal zones: medial, lateral, ventral, dorsal) and 168.14 ± 65.54 mg/cm (range 17.47-208.97 mg/cm) for healthy bone tissue (femur and tibia).

CONCLUSION

Based on WOMAC scores, LEFS, ambulatory status, and quality of life findings, it can be concluded that following tibial head ORIF with allograft bone patients has promising results.

摘要

背景

为了确定在胫骨头骨折切开复位内固定(ORIF)中使用同种异体骨移植治疗的患者的临床结果。

方法

纳入接受切开复位内固定(ORIF)并用同种异体人股骨头治疗内侧、外侧或双髁胫骨平台骨折的患者。邀请患者提供以下信息:西部安大略省和麦克马斯特大学骨关节炎指数(WOMAC)、欧洲五维健康量表评分(EQ-5D)、下肢功能量表(LEFS)和帕克运动评分。同种异体骨区域和健康人骨组织的骨矿物质密度(BMD)通过定量计算机断层扫描进行测量。

结果

本研究共纳入 22 例患者,平均随访时间为 2.88±2.46 年。本研究中最常见的骨折类型为 Schatzker II 型(11 例,50.0%)或 AO/OTA 41.B3 型(12 例,54.5%)骨折。术后 WOMAC 总分为 13.0(IQR=16.3,范围 0-33)。中位生活质量(EQ-5D)评分为 0.887±0.121(范围 0.361-1.000)。中位下肢功能量表(LEFS)评分为 57.5±19.0(范围 33-79)。平均帕克运动评分 9(范围 6-9)。全组中位数骨矿物质密度(BMD)为 300.04±226.02mg/cm(范围-88.68 至 555.06mg/cm)(ROI5)(中央),214.80±167.45mg/cm(范围-7.16 至 597.21mg/cm)(ROI1-4)(边缘区:内侧、外侧、腹侧、背侧)和 168.14±65.54mg/cm(范围 17.47-208.97mg/cm)(健康骨组织(股骨和胫骨)。

结论

根据 WOMAC 评分、LEFS、活动状态和生活质量发现,可得出结论,胫骨头 ORIF 后使用同种异体骨移植治疗的患者具有良好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d631/10110662/25863ce01670/402_2022_4461_Fig1_HTML.jpg

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