儿童小脑蚓部髓母细胞瘤全切除术后并发小脑缄默症伴多食。
A case of postoperative cerebellar mutism with hyperphagia in a child following gross total resection of medulloblastoma occupying the cerebellar vermis.
机构信息
Department of Neurosciences, King Faisal Specialist Hospital and Research Center, Makkah Al Mukarramah Branch Rd, Al Mathar Ash Shamali, Riyadh, Riyadh Province, 11564, Saudi Arabia.
College of Medicine, King Saud University Medical City, Alshaikh Hassan A. Alshaikh St., Riyadh, Riyadh Province, 12372, Saudi Arabia.
出版信息
Childs Nerv Syst. 2022 Nov;38(11):2189-2198. doi: 10.1007/s00381-022-05520-9. Epub 2022 May 10.
INTRODUCTION
Cerebellar mutism syndrome is a well-known complication following posterior fossa tumor resection. Its incidence is markedly increased among patients with medulloblastoma. Patients typically present with an inability to communicate verbally due to disruption of the dentato-thalamocortical pathway.
CASE DESCRIPTION
We present a unique case of cerebellar mutism in a three-year-old girl who underwent gross total resection of medulloblastoma occupying the cerebellar vermis. In addition to mutism, the patient developed hyperphagia.
DISCUSSION
This case report aims to contribute to current understanding of the role of cerebello-hypothalamic connections in cerebellar mutism and their clinical significance.
简介
小脑缄默症是一种众所周知的后颅窝肿瘤切除术后的并发症。在髓母细胞瘤患者中，其发病率显著增加。由于齿状核-丘脑-皮质通路的中断，患者通常表现为无法进行言语交流。
病例描述
我们报告了一例三岁女孩的小脑缄默症，该女孩患有占据小脑蚓部的髓母细胞瘤，行大体全切除术后出现小脑缄默症。除了缄默症外，该患者还出现了食欲过盛。
讨论
本病例报告旨在为目前对小脑-下丘脑连接在小脑缄默症中的作用及其临床意义的理解做出贡献。
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