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腹腔镜 Roux-en-Y 胃旁路手术治疗肥胖症后短或长胆胰支长度的影响:倾向评分匹配分析。

Effects of short or long biliopancreatic limb length after laparoscopic Roux-en-Y gastric bypass surgery for obesity: a propensity score-matched analysis.

机构信息

Department of General and Visceral Surgery, Lucerne Cantonal Hospital, Lucerne, Switzerland.

Department of Surgery, Lugano Regional Hospital, Lugano, Switzerland.

出版信息

Langenbecks Arch Surg. 2022 Sep;407(6):2319-2326. doi: 10.1007/s00423-022-02537-1. Epub 2022 May 10.

Abstract

PURPOSE

Although recent studies reported superior weight reduction in patients undergoing Roux-en-Y gastric bypass (RYGB) with long biliopancreatic limb (BPL), no recommendation regarding limb lengths exists. This study compares weight loss and resolution of obesity-related comorbidities in patients undergoing RYGB with either long or short BPL.

METHODS

A retrospective data search from medical records was performed. A total of 308 patients underwent laparoscopic RYGB with a BPL length of either 100 cm or 50 cm. Data was analyzed before and after propensity score matching.

RESULTS

No statistically significant difference in weight reduction between long and short BPL RYGB in terms of percentage of excess weight loss (%EWL) (86.4 ± 24.5 vs. 83.4 ± 21.4, p = 0.285) and percentage of total weight loss (%TWL) (32.4 ± 8.4 vs. 33.0 ± 8.3, p = 0.543) was found 24 months after surgery. Propensity score-matched analysis did not show any statistically significant difference between groups in both %EWL and %TWL. No significant difference between long and short BPL RYGB in the resolution of obesity-related comorbidities was noted 24 months after surgery.

CONCLUSION

Weight loss and resolution of obesity-related comorbidities were not significantly different between long and short BPL RYGB 24 months after surgery.

摘要

目的

尽管最近的研究报告称,接受 Roux-en-Y 胃旁路术(RYGB)联合长胆胰支(BPL)的患者体重减轻效果更好,但目前尚无关于支臂长度的推荐。本研究比较了接受 RYGB 联合长或短 BPL 的患者的减重效果和肥胖相关合并症的缓解情况。

方法

对病历进行回顾性数据检索。共有 308 例患者接受腹腔镜 RYGB 手术,BPL 长度为 100cm 或 50cm。在进行倾向评分匹配之前和之后进行数据分析。

结果

术后 24 个月,长、短 BPL RYGB 在超重减轻百分比(%EWL)(86.4±24.5% vs. 83.4±21.4%,p=0.285)和总体重减轻百分比(%TWL)(32.4±8.4% vs. 33.0±8.3%,p=0.543)方面的减重效果无统计学差异。术后 24 个月,倾向评分匹配分析显示两组在%EWL 和%TWL 方面均无统计学差异。术后 24 个月,长、短 BPL RYGB 在肥胖相关合并症的缓解方面无显著差异。

结论

术后 24 个月,长、短 BPL RYGB 的体重减轻和肥胖相关合并症的缓解效果无显著差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bae/9468033/69596683fc82/423_2022_2537_Fig1_HTML.jpg

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