Nijland Leontien M G, van Sabben Joris M, Marsman Hendrik A, van Veen Ruben N, de Castro Steve M M
Department of Surgery, OLVG Hospital, Jan Tooropstraat 164, 1061 AE, Amsterdam, The Netherlands.
Obes Surg. 2021 Nov;31(11):4846-4852. doi: 10.1007/s11695-021-05651-z. Epub 2021 Aug 9.
In order to design the most effective weight loss procedure, the ideal biliopancreatic limb (BPL) and alimentary limb (AL) length in Roux-en-Y gastric bypass (RYGB) have been discussed extensively. Yet, no consensus has been reached. The aim of this study was to compare weight loss after a short and long BPL in patients who underwent a RYGB with a minimum of 4 years follow-up.
This retrospective cohort study consisted of 574 patients who underwent a primary RYGB procedure between March 2015 and January 2017. Patients were divided in two groups based on the surgical procedure performed: a short BPL group (BPL of 50 cm with an AL of 150 cm) and long BPL group (BPL of 150 cm with an AL of 75 cm). The percentage total weight loss (%TWL) between groups was compared up to 4 years after surgery. Secondary outcomes were 30-day postoperative complications and health-related quality of life (RAND-36).
The short BPL group consisted of 286 patient and the long BPL group of 288 patients. Follow-up rates of both groups at the first, second, third, and fourth year after surgery were comparable. The long BPL group showed significantly more %TWL compared to the short BP limb group starting at 6 months (p = 0.004) until 4 years after surgery (p < 0.001). Thirty-day complications and health-related quality of life did not differ.
The results showed significantly more %TWL in patients receiving a long BPL compared to the short BPL up to 4 years after surgery.
为了设计出最有效的减肥手术方案,人们广泛讨论了Roux-en-Y胃旁路术(RYGB)中理想的胆胰支(BPL)和消化道支(AL)长度。然而,尚未达成共识。本研究的目的是比较接受RYGB且随访至少4年的患者中,短BPL和长BPL术后的体重减轻情况。
这项回顾性队列研究纳入了2015年3月至2017年1月期间接受初次RYGB手术的574例患者。根据手术方式将患者分为两组:短BPL组(BPL为50厘米,AL为150厘米)和长BPL组(BPL为150厘米,AL为75厘米)。比较两组术后4年内的总体重减轻百分比(%TWL)。次要结局包括术后30天并发症和健康相关生活质量(RAND-36)。
短BPL组有286例患者,长BPL组有288例患者。两组在术后第一、二、三、四年的随访率相当。从术后6个月(p = 0.004)到术后4年(p < 0.001),长BPL组的%TWL显著高于短BPL组。术后30天并发症和健康相关生活质量无差异。
结果显示,术后4年内,接受长BPL的患者的%TWL显著高于接受短BPL的患者。