Haga Mitsuhiro, Motojima Yukiko, Masuda Wataru, Fujino Takashi, Tamaru Jun-Ichi, Nakamura Takumi, Oya Soichi, Amikura Takayuki, Higashino Masahiko, Kanai Masayo, Moriwaki Koichi
Departments of Pediatrics.
Pathology.
J Pediatr Hematol Oncol. 2023 Jan 1;45(1):e135-e138. doi: 10.1097/MPH.0000000000002474. Epub 2022 May 3.
Primitive myxoid mesenchymal tumor of infancy (PMMTI) is a rare soft tissue sarcoma in childhood. We present the case of a newborn male who experienced a severe hemorrhage in utero from the tumor on the scalp. He died at the age of 24 hours owing to hemorrhagic shock. The tumor was posthumously diagnosed as PMMTI. A literature search indicated that cases of severe hemorrhage from soft tissue sarcomas in utero or at birth are limited to infantile fibrosarcoma. This is the first case of PMMTI with massive hemorrhage. Clinicians must be aware of hemorrhagic complications of PMMTI.
婴儿原始黏液样间叶性肿瘤（PMMTI）是儿童期一种罕见的软组织肉瘤。我们报告一例新生儿男性病例，其在子宫内时头皮肿瘤发生严重出血。他因失血性休克于24小时龄时死亡。该肿瘤在死后被诊断为PMMTI。文献检索表明，子宫内或出生时软组织肉瘤发生严重出血的病例仅限于婴儿纤维肉瘤。这是首例伴有大量出血的PMMTI病例。临床医生必须意识到PMMTI的出血并发症。
