微生物组：一种肠道细菌如何促进线虫更健康的生活。

Microbiomes: How a gut bacterium promotes healthier living in a nematode.

机构信息

Department of Biochemistry and Biomedical Sciences, Michael G. DeGroote Institute for Infectious Disease Research, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON L8S 4L8, Canada.

出版信息

Curr Biol. 2022 May 9;32(9):R428-R430. doi: 10.1016/j.cub.2022.04.008.

DOI:10.1016/j.cub.2022.04.008

PMID:35537396

Abstract

A new study finds that a bacterium from the microbiome of the nematode Pristionchus pacificus can promote rapid growth, increased body size, and increased fecundity by inducing neuronal expression of TGF-β ligands. This is an intriguing example of how the microbiota induces systemic effects in the host by stimulating neuroendocrine signaling.

摘要

一项新的研究发现，秀丽隐杆线虫肠道微生物组中的一种细菌可以通过诱导 TGF-β 配体在神经元中的表达来促进快速生长、增加体型和提高繁殖力。这是一个有趣的例子，说明了微生物组如何通过刺激神经内分泌信号来诱导宿主的全身效应。