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抑郁症状与精神病样本中认知行为治疗接受度之间的关联:一项横断面研究。

Association between depressive symptoms and cognitive-behavioural therapy receipt within a psychosis sample: a cross-sectional study.

机构信息

Division of Psychiatry, University College London, London, UK

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

出版信息

BMJ Open. 2022 May 10;12(5):e051873. doi: 10.1136/bmjopen-2021-051873.

Abstract

OBJECTIVES

To examine whether depressive symptoms predict receipt of cognitive-behavioural therapy for psychosis (CBTp) in individuals with psychosis.

DESIGN

Retrospective cross-sectional analysis of electronic health records (EHRs) of a clinical cohort.

SETTING

A secondary National Health Service mental healthcare service serving four boroughs of south London, UK.

PARTICIPANTS

20 078 patients diagnosed with an International Classification of Diseases, version 10 (ICD-10) code between F20 and 29 extracted from an EHR database.

PRIMARY AND SECONDARY OUTCOME MEASURES

Primary: Whether recorded depressive symptoms predicted CBTp session receipt, defined as at least one session of CBTp identified from structured EHR fields supplemented by a natural language processing algorithm. Secondary: Whether age, gender, ethnicity, symptom profiles (positive, negative, manic and disorganisation symptoms), a comorbid diagnosis of depression, anxiety or bipolar disorder, general CBT receipt prior to the primary psychosis diagnosis date or type of psychosis diagnosis predicted CBTp receipt.

RESULTS

Of patients with a psychotic disorder, only 8.2% received CBTp. Individuals with at least one depressive symptom recorded, depression symptom severity and 12 out of 15 of the individual depressive symptoms independently predicted CBTp receipt. Female gender, White ethnicity and presence of a comorbid affective disorder or primary schizoaffective diagnosis were independently positively associated with CBTp receipt within the whole sample and the top 25% of mentioned depressive symptoms.

CONCLUSIONS

Individuals with a psychotic disorder who had recorded depressive symptoms were significantly more likely to receive CBTp sessions, aligning with CBTp guidelines of managing depressive symptoms related to a psychotic experience. However, overall receipt of CBTp is low and more common in certain demographic groups, and needs to be increased.

摘要

目的

探讨抑郁症状是否能预测精神病患者接受认知行为疗法治疗(CBTp)。

设计

对临床队列电子健康记录(EHR)的回顾性横断面分析。

设置

英国伦敦南部四个行政区的二级国家卫生服务精神保健服务。

参与者

从 EHR 数据库中提取的国际疾病分类第 10 版(ICD-10)代码为 F20 至 29 的 20078 例患者被诊断患有精神病。

主要和次要结果测量

主要:记录的抑郁症状是否预测 CBTp 疗程的接受,定义为从结构化 EHR 字段中确定至少一次 CBTp 疗程,并辅以自然语言处理算法。次要:年龄、性别、种族、症状特征(阳性、阴性、躁狂和紊乱症状)、抑郁、焦虑或双相情感障碍的合并诊断、在首发精神病诊断日期之前接受的一般 CBT、或精神病诊断类型是否预测 CBTp 的接受。

结果

在患有精神病的患者中,只有 8.2%接受了 CBTp。记录至少有一种抑郁症状、抑郁症状严重程度和 15 种抑郁症状中的 12 种独立预测了 CBTp 的接受。女性、白种人、合并情感障碍或首发精神分裂情感性诊断与整个样本和前 25%的抑郁症状中 CBTp 的接受独立呈正相关。

结论

记录有抑郁症状的精神病患者更有可能接受 CBTp 疗程,这与 CBTp 管理与精神病体验相关的抑郁症状的指南一致。然而,总体上 CBTp 的接受率较低,且在某些人群中更为常见,需要增加。

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