Pedro Ernesto University Hospital, State University of Rio de Janeiro (UERJ), Boulevard 28 de Setembro, 77, Vila Isabel, Rio de Janeiro, 20551-030, Brazil.
Medical Sciences Post-Graduation Program, School of Medical Sciences, State University of Rio de Janeiro (UERJ), Av. Prof. Manoel de Abreu, 444, 2º andar, Vila Isabel, Rio de Janeiro, 20550-170, Brazil.
BMC Res Notes. 2022 May 10;15(1):158. doi: 10.1186/s13104-022-06047-7.
The advent of new techniques such as video-assisted thoracoscopic surgery (VATS) for the removal of lung segments leads to compression of the surgical specimen, with the possible dissemination of neoplastic cells. The sheer volume of surgeries performed using these techniques has caused many institutions to stop removing the surgical specimen using an endobag, even when retractors/protectors are used in the instrumentalization incision. This study aimed to collect data from patients undergoing lung resection by VATS and analyze the cytopathological results of the collected material.
A total of 47 endobag fluid samples were collected from patients who underwent VATS. The surgical specimen was subjected to histopathological analysis, and all patients underwent pathological TNM staging. In the cytopathological analyses, only 2 (4.3%) specimens of endobag fluid aspirate were positive for neoplastic cells. In these two cases, the tumors were peripheral, both with diagnoses of moderately differentiated adenocarcinoma and with classifications of T1bN0M0 and T3N0M0. These results indicate that although there is a low incidence of tumor cells in endobag fluid, it is always better to perform surgery using all available protective measures to avoid tumor implantation in the thoracic cavity to the greatest extent possible.
随着视频辅助胸腔镜手术（VATS）等新技术用于肺段切除，手术标本受到挤压，可能导致肿瘤细胞扩散。由于这些技术的手术量很大，许多机构甚至在器械化切口使用牵开器/保护器时，也停止使用标本外袋来取出手术标本。本研究旨在收集接受 VATS 肺切除术的患者数据，并分析收集材料的细胞病理学结果。
共从接受 VATS 的患者中收集了 47 份标本外袋液样本。对手术标本进行组织病理学分析，所有患者均进行了病理 TNM 分期。在细胞病理学分析中，仅 2（4.3%）份标本外袋液抽吸物的肿瘤细胞呈阳性。在这两例中，肿瘤均为外周性，均诊断为中分化腺癌，分类为 T1bN0M0 和 T3N0M0。这些结果表明，尽管标本外袋液中肿瘤细胞的发生率较低，但始终最好使用所有可用的保护措施进行手术，以最大程度地避免肿瘤在胸腔内种植。
