健康促进、疾病预防与治疗的候选植物：芸香（L.），传统医学中的一种重要药用植物。

A Candidate for Health Promotion, Disease Prevention and Treatment: Common Rue ( L.), an Important Medicinal Plant in Traditional Medicine.

作者信息

Shahrajabian Mohamad Hesam

机构信息

Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.

出版信息

Curr Rev Clin Exp Pharmacol. 2023;19(1):2-11. doi: 10.2174/2772432817666220510143902.

DOI:10.2174/2772432817666220510143902

PMID:35538827

Abstract

BACKGROUND

Ruta graveolens L. belongs to Rutaceae; it is a semi-wood perennial or a small evergreen sub-shrub, which is native to Southern Europe, West Asia and Northern Africa.

OBJECTIVE

The goal of this manuscript was to outline the most notable traditional and modern advantages and pharmaceutical benefits of common rue.

METHODS

The manuscript covers review articles, randomized control experiments, analytical studies and observations, which have been gathered from different sources, such as Google Scholar, Scopus, Science Direct and PubMed. A review of the literature was carried out using the keywords rutin, L., rue, common rune, coumarin, natural products and pharmaceutical benefits.

RESULTS

Rue contains quinoline alkaloids, such as graveoline and graveolinine, acridone alkaloids, such as furacridone and gravacridone, furanoquinoline dictamnine, coumarins, such as gravelliferone, isorutarin, rutacultin, rutaretin, and suberenone, and the furanocoumarins 5-methoxypsoralen (bergapten) and 8-methoxypsoralen (xanthotoxine). Most of its aromatic and medicinal properties are due to the presence of rutin and its essential oil. It has been used in folk medicine as a stimulant, for its antiinflammatory and analgesic properties, anti-androgenic activity, anti-hyperglycemic effects, antihyperlipidemic effects, xanthine oxidase inhibition activity, and anticancer properties.

CONCLUSION

According to pharmacological and phytochemical advantages, pennyroyal shows its importance as a medicinal plant in both modern medicinal science and traditional medicine.

摘要

背景

芸香属于芸香科；它是一种半木质多年生植物或小型常绿亚灌木，原产于南欧、西亚和北非。

目的

本手稿的目的是概述普通芸香最显著的传统和现代优势及药用价值。

方法

本手稿涵盖了综述文章、随机对照实验、分析研究和观察结果，这些内容来自不同来源，如谷歌学术、Scopus、科学Direct和PubMed。使用关键词芦丁、芸香、普通芸香、香豆素、天然产物和药用价值对文献进行了综述。

结果

芸香含有喹啉生物碱，如芸香碱和芸香宁碱，吖啶酮生物碱，如呋喃吖啶酮和重吖啶酮，呋喃喹啉白鲜碱，香豆素，如芸香独活素、异芸香苷、芸香苦素、芸香黄素和软木酮，以及呋喃香豆素5-甲氧基补骨脂素（佛手柑内酯）和8-甲氧基补骨脂素（花椒毒素）。其大部分芳香和药用特性归因于芦丁及其精油的存在。它在民间医学中被用作兴奋剂，因其具有抗炎、镇痛特性、抗雄激素活性、抗高血糖作用、抗高血脂作用、黄嘌呤氧化酶抑制活性和抗癌特性。