单取代硼二吡咯（BODIPY）与HFBI-RGD的自组装。
The self-assembly of monosubstituted BODIPY and HFBI-RGD.
作者信息
Sun Fengnan, Yang Guang, Zhang Qian, Xue Zhongbo, Gu Chengzhi, Chen Zhuozhi, Yan Boying, Feng Yaqing, Wang Zefang, Meng Shuxian
机构信息
School of Chemical Engineering and Technology, Tianjin University Tianjin 300050 China
Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072 China.
出版信息
RSC Adv. 2018 Jun 12;8(38):21472-21479. doi: 10.1039/c8ra03687j. eCollection 2018 Jun 8.
Abstract
A novel fluorescent probe was constructed by the self-assembly of monosubstituted BODIPY and a novel targeted hydrophobin named hereafter as HFBI-RGD. Optical measurements and theoretical calculations confirmed that the spectral properties of the probe were greatly influenced by the BODIPY structure, the appropriate volume of BODIPY and the cavity of HFBI-RGD. The experiments and demonstrated that the probe had excellent ability for tumor labelling.
摘要
通过单取代BODIPY与一种新的靶向疏水蛋白（以下简称HFBI-RGD）的自组装构建了一种新型荧光探针。光学测量和理论计算证实，该探针的光谱性质受到BODIPY结构、BODIPY的适当体积以及HFBI-RGD的空腔的极大影响。实验表明该探针具有出色的肿瘤标记能力。
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