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用于显著增强乳酸检测的全氟磺酸(Nafion®)涂层介孔钯膜

Nafion®-coated mesoporous Pd film toward remarkably enhanced detection of lactic acid.

作者信息

Baba Daisuke, Nugraha Asep Sugih, Iqbal Muhammad, Bo Jiang, Li Cuiling, Alshehri Abdulmohsen Ali, You Jungmok, Malgras Victor, Yamachi Yusuke, Asahi Toru

机构信息

International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS) 1-1 Namiki Tsukuba Ibaraki 305-0044 Japan

Faculty of Science and Engineering, Waseda University 3-4-1 Okubo, Shinjuku Tokyo 169-8555 Japan.

出版信息

RSC Adv. 2018 Mar 14;8(19):10446-10449. doi: 10.1039/c7ra13026k. eCollection 2018 Mar 13.

Abstract

Mesoporous metal films can detect biomarkers with high sensitivity. Further coating the mesoporous metal with polymers enhances sensing selectivity by favoring specific biomarkers against other interferents. In the present study, we report the fabrication of a Nafion®-coated mesoporous Pd film to filtrate interferents present in sweat during non-invasive biosensing. By using a Nafion®-coated mesoporous Pd film, lactic acid, a metabolite present in sweat, can be successfully detected with high sensitivity.

摘要

介孔金属薄膜能够高灵敏度地检测生物标志物。用聚合物进一步包覆介孔金属,通过优先选择特定生物标志物而排斥其他干扰物来提高传感选择性。在本研究中,我们报道了一种用于在无创生物传感过程中过滤汗液中存在的干扰物的涂覆有Nafion®的介孔钯薄膜的制备方法。通过使用涂覆有Nafion®的介孔钯薄膜,能够成功地高灵敏度检测汗液中存在的代谢物乳酸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/767b/9078978/f8099881415b/c7ra13026k-f1.jpg

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