用于选择性和安全癌症诊疗的基于黄连素的碳点

Berberine-based carbon dots for selective and safe cancer theranostics.

作者信息

Zhang Fan, Zhang Ming, Zheng Xiao, Tao Songyuan, Zhang Zhanqiang, Sun Madi, Song Yubin, Zhang Jing, Shao Dan, He Kan, Li Jing, Yang Bai, Chen Li

机构信息

Department of Pharmacology, Nanomedicine Engineering Laboratory of Jilin Province, College of Basic Medical Sciences, Jilin University Changchun 130021 China

State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University Changchun 130012 P. R. China

出版信息

RSC Adv. 2018 Jan 3;8(3):1168-1173. doi: 10.1039/c7ra12069a. eCollection 2018 Jan 2.

Fluorescent berberine-based carbon dots (Ber-CDs) were prepared through a facile synthesis strategy. Ber-CDs exhibited excellent optical properties for bioimaging and retained the biofunctions of berberine, and enabled selective and safe anti-tumor performance, demonstrating their promising application potential in cancer theranostics.