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用于选择性和安全癌症诊疗的基于黄连素的碳点

Berberine-based carbon dots for selective and safe cancer theranostics.

作者信息

Zhang Fan, Zhang Ming, Zheng Xiao, Tao Songyuan, Zhang Zhanqiang, Sun Madi, Song Yubin, Zhang Jing, Shao Dan, He Kan, Li Jing, Yang Bai, Chen Li

机构信息

Department of Pharmacology, Nanomedicine Engineering Laboratory of Jilin Province, College of Basic Medical Sciences, Jilin University Changchun 130021 China

State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University Changchun 130012 P. R. China

出版信息

RSC Adv. 2018 Jan 3;8(3):1168-1173. doi: 10.1039/c7ra12069a. eCollection 2018 Jan 2.

DOI:10.1039/c7ra12069a
PMID:35540876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9076993/
Abstract

Fluorescent berberine-based carbon dots (Ber-CDs) were prepared through a facile synthesis strategy. Ber-CDs exhibited excellent optical properties for bioimaging and retained the biofunctions of berberine, and enabled selective and safe anti-tumor performance, demonstrating their promising application potential in cancer theranostics.

摘要

通过一种简便的合成策略制备了基于荧光黄连素的碳点（Ber-CDs）。Ber-CDs在生物成像方面表现出优异的光学性能，保留了黄连素的生物功能，并具有选择性和安全性的抗肿瘤性能，展示了它们在癌症诊疗中的广阔应用潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/232f4aa4b6ce/c7ra12069a-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/f68fa080995f/c7ra12069a-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/2cb202e5e1d3/c7ra12069a-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/b9b1604c191e/c7ra12069a-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/dc6bb5843f94/c7ra12069a-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/232f4aa4b6ce/c7ra12069a-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/f68fa080995f/c7ra12069a-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/2cb202e5e1d3/c7ra12069a-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/b9b1604c191e/c7ra12069a-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/dc6bb5843f94/c7ra12069a-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7d/9076993/232f4aa4b6ce/c7ra12069a-f4.jpg

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