• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在集中式抗凝门诊优化直接口服抗凝剂管理服务

Optimization of DOAC management services in a centralized anticoagulation clinic.

作者信息

Sylvester Katelyn W, Chen Alisia, Lewin Andrea, Fanikos John, Goldhaber Samuel Z, Connors Jean M

机构信息

Department of Pharmacy Services Brigham and Women's Hospital Boston Massachusetts USA.

Bouve College of Health Sciences Northeastern University Boston Massachusetts USA.

出版信息

Res Pract Thromb Haemost. 2022 May 5;6(3):e12696. doi: 10.1002/rth2.12696. eCollection 2022 Mar.

DOI:10.1002/rth2.12696
PMID:35541695
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9069544/
Abstract

BACKGROUND

In 2017, the Brigham and Women's Hospital Anticoagulation Management Service (BWH AMS) expanded services to patients on direct oral anticoagulants (DOACs). We have since updated our DOAC management plan and adjusted the workflow of our clinic.

OBJECTIVES

This report describes how our DOAC management has evolved and describes key interventions made. Additionally, we report on the results of a survey completed by referring physicians that assessed perspectives regarding centralized DOAC management by BWH AMS pharmacists.

METHODS

An analysis was completed of all patients referred to the BWH AMS and the number of interventions completed and documented in our anticoagulation management software. A survey with eight questions was sent to 110 referring physicians (selected based on referring to the AMS within the past 1.5 years).

RESULTS

Over 4 years, 1622 patients on DOACs were referred to the BWH AMS, amounting to 3154 DOAC encounters. A total of 212 interventions for medication procurement, 171 dose adjustment interventions, and 603 coordinated procedure plans were completed. Of the 32 physicians who responded to the survey, many believed that the quality and safety of anticoagulation therapy was improved with BWH AMS management. Despite provider satisfaction with pharmacist-led care in DOACs, physicians expressed concerns regarding the lack of provider awareness of the clinic and possible duplicative efforts.

CONCLUSION

We plan to evolve the DOAC clinic model to optimize its clinical and operational value and to improve our delivery of care using electronic tools to move toward a population management approach for DOAC management.

摘要

背景

2017年,布莱根妇女医院抗凝管理服务部(BWH AMS)将服务扩展至使用直接口服抗凝剂(DOAC)的患者。自那时起,我们更新了DOAC管理计划并调整了诊所的工作流程。

目的

本报告描述了我们的DOAC管理如何演变,并介绍了所采取的关键干预措施。此外,我们报告了转诊医生完成的一项调查结果,该调查评估了他们对BWH AMS药剂师集中式DOAC管理的看法。

方法

对所有转诊至BWH AMS的患者以及在我们的抗凝管理软件中完成并记录的干预措施数量进行了分析。向110名转诊医生(根据过去1.5年内转诊至AMS的情况选择)发送了一份包含八个问题的调查问卷。

结果

在4年多的时间里,1622名使用DOAC的患者被转诊至BWH AMS,共计3154次DOAC诊疗。共完成了212次药物采购干预、171次剂量调整干预以及603次协调程序计划。在32名回复调查问卷的医生中,许多人认为BWH AMS管理提高了抗凝治疗的质量和安全性。尽管医生对药剂师主导的DOAC护理感到满意,但他们对诊所缺乏医生认知以及可能存在的重复工作表示担忧。

结论

我们计划改进DOAC诊所模式,以优化其临床和运营价值,并利用电子工具改进我们的护理服务,朝着DOAC管理的人群管理方法迈进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/982a/9069544/2a438b0d91e3/RTH2-6-e12696-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/982a/9069544/2a438b0d91e3/RTH2-6-e12696-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/982a/9069544/2a438b0d91e3/RTH2-6-e12696-g001.jpg

相似文献

1
Optimization of DOAC management services in a centralized anticoagulation clinic.在集中式抗凝门诊优化直接口服抗凝剂管理服务
Res Pract Thromb Haemost. 2022 May 5;6(3):e12696. doi: 10.1002/rth2.12696. eCollection 2022 Mar.
2
Atrial Fibrillation Patients on Warfarin and Their Transition to Direct Oral Anticoagulants.华法林抗凝治疗的心房颤动患者及其向直接口服抗凝剂的转换。
Crit Pathw Cardiol. 2021 Jun 1;20(2):103-107. doi: 10.1097/HPC.0000000000000251.
3
Expanding anticoagulation management services to include direct oral anticoagulants.扩大抗凝管理服务范围,纳入直接口服抗凝剂。
J Thromb Thrombolysis. 2018 Feb;45(2):274-280. doi: 10.1007/s11239-017-1602-1.
4
The role of clinical pharmacy anticoagulation services in direct oral anticoagulant monitoring.临床药学抗凝服务在直接口服抗凝剂监测中的作用。
J Thromb Thrombolysis. 2020 Oct;50(3):739-745. doi: 10.1007/s11239-020-02064-0.
5
The Impact of Clinical Pharmacy Services on Direct Oral Anticoagulant Medication Selection and Dosing in the Ambulatory Care Setting.临床药学服务对门诊护理环境中直接口服抗凝药物选择和剂量的影响。
J Pharm Pract. 2024 Jun;37(3):671-676. doi: 10.1177/08971900231166555. Epub 2023 Mar 29.
6
Trends in anticoagulation management services following incorporation of direct oral anticoagulants at a large academic medical center.大型学术医疗中心纳入直接口服抗凝剂后抗凝管理服务的趋势。
J Thromb Thrombolysis. 2021 May;51(4):1050-1058. doi: 10.1007/s11239-020-02286-2. Epub 2020 Oct 9.
7
Pharmacist monitoring of direct oral anticoagulants for American Indians and Alaska Natives in the outpatient setting.门诊环境中药剂师对美国印第安人和阿拉斯加原住民直接口服抗凝剂的监测。
J Am Pharm Assoc (2003). 2022 Mar-Apr;62(2):598-603. doi: 10.1016/j.japh.2021.10.009. Epub 2021 Oct 14.
8
Assessment of a Pharmacist-Led Direct Oral Anticoagulant Monitoring Clinic.药剂师主导的直接口服抗凝剂监测门诊评估
Can J Hosp Pharm. 2021 Winter;74(1):7-14. Epub 2021 Jan 1.
9
A scoping review of direct oral anticoagulant ambulatory management practices.直接口服抗凝剂门诊管理实践的范围综述
J Thromb Thrombolysis. 2023 May;55(4):700-709. doi: 10.1007/s11239-023-02794-x. Epub 2023 Mar 28.
10
Multicomponent Pharmacist Intervention Did Not Reduce Clinically Important Medication Errors for Ambulatory Patients Initiating Direct Oral Anticoagulants.多组分药剂师干预并未减少起始直接口服抗凝剂的门诊患者的临床重要药物差错。
J Gen Intern Med. 2023 Dec;38(16):3526-3534. doi: 10.1007/s11606-023-08315-z. Epub 2023 Sep 27.

引用本文的文献

1
Evaluation of gaps in direct oral anticoagulants (DOACs) management in an outpatient underserved clinic: a cross-sectional study.门诊医疗服务不足诊所中直接口服抗凝剂(DOACs)管理差距的评估:一项横断面研究。
Sci Rep. 2025 Jul 2;15(1):23064. doi: 10.1038/s41598-025-07712-0.
2
Safe and effective anticoagulation use: case studies in anticoagulation stewardship.安全有效的抗凝治疗应用:抗凝管理案例研究
J Thromb Haemost. 2025 Mar;23(3):779-789. doi: 10.1016/j.jtha.2024.11.024. Epub 2024 Dec 10.
3
Assessment of Population-Based Approach to Direct Oral Anticoagulant Management.

本文引用的文献

1
Shifting the Paradigm: A Population Health Approach to the Management of Direct Oral Anticoagulants.转变范式:直接口服抗凝剂管理的人群健康方法。
J Am Heart Assoc. 2021 Dec 21;10(24):e022758. doi: 10.1161/JAHA.121.022758. Epub 2021 Nov 19.
2
Association between Cerebral Infarction Risk and Medication Adherence in Atrial Fibrillation Patients Taking Direct Oral Anticoagulants.服用直接口服抗凝剂的心房颤动患者脑梗死风险与药物依从性之间的关联
Healthcare (Basel). 2021 Oct 1;9(10):1313. doi: 10.3390/healthcare9101313.
3
Factors associated with primary nonadherence to newly initiated direct oral anticoagulants in patients with nonvalvular atrial fibrillation.
基于人群的直接口服抗凝剂管理方法评估
J Pharm Technol. 2024 Apr;40(2):72-77. doi: 10.1177/87551225231226431. Epub 2024 Jan 20.
4
Bleeding related to oral anticoagulants: Trends in US emergency department visits, 2016-2020.与口服抗凝剂相关的出血:2016-2020 年美国急诊科就诊趋势。
Thromb Res. 2023 May;225:110-115. doi: 10.1016/j.thromres.2023.03.010. Epub 2023 Mar 29.
5
A call to action for anticoagulation stewardship.抗凝管理的行动呼吁。
Res Pract Thromb Haemost. 2022 Jul 17;6(5):e12757. doi: 10.1002/rth2.12757. eCollection 2022 Jul.
6
Are outpatient anticoagulation management services the wave of the future (again)?门诊抗凝管理服务会再次成为未来的潮流吗?
Res Pract Thromb Haemost. 2022 May 30;6(4):e12735. doi: 10.1002/rth2.12735. eCollection 2022 May.
与非瓣膜性心房颤动患者新起始直接口服抗凝剂原发性不依从相关的因素。
J Manag Care Spec Pharm. 2021 Sep;27(9):1210-1220. doi: 10.18553/jmcp.2021.27.9.1210.
4
Antithrombosis stewardship efforts to de-escalate inappropriate combined therapy in outpatient clinics.抗血栓管理工作旨在降低门诊中不适当联合治疗的使用。
J Thromb Thrombolysis. 2022 Feb;53(2):436-445. doi: 10.1007/s11239-021-02551-y. Epub 2021 Aug 19.
5
Trends in anticoagulation management services following incorporation of direct oral anticoagulants at a large academic medical center.大型学术医疗中心纳入直接口服抗凝剂后抗凝管理服务的趋势。
J Thromb Thrombolysis. 2021 May;51(4):1050-1058. doi: 10.1007/s11239-020-02286-2. Epub 2020 Oct 9.
6
Real-World Adherence and Persistence to Direct Oral Anticoagulants in Patients With Atrial Fibrillation: A Systematic Review and Meta-Analysis.心房颤动患者对直接口服抗凝剂的真实世界依从性和持续性:一项系统评价和荟萃分析。
Circ Cardiovasc Qual Outcomes. 2020 Mar;13(3):e005969. doi: 10.1161/CIRCOUTCOMES.119.005969. Epub 2020 Mar 9.
7
How I assess and manage the risk of bleeding in patients treated for venous thromboembolism.我如何评估和管理接受静脉血栓栓塞治疗患者的出血风险。
Blood. 2020 Mar 5;135(10):724-734. doi: 10.1182/blood.2019001605.
8
Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: ASCO Clinical Practice Guideline Update.静脉血栓栓塞症预防和治疗癌症患者:ASCO 临床实践指南更新。
J Clin Oncol. 2020 Feb 10;38(5):496-520. doi: 10.1200/JCO.19.01461. Epub 2019 Aug 5.
9
2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons.2019年美国心脏协会/美国心脏病学会/心律学会对2014年美国心脏协会/美国心脏病学会/心律学会心房颤动患者管理指南的聚焦更新:美国心脏病学会/美国心脏协会临床实践指南工作组和心律学会与胸外科医师协会合作报告
Circulation. 2019 Jul 9;140(2):e125-e151. doi: 10.1161/CIR.0000000000000665. Epub 2019 Jan 28.
10
Overcoming barriers to integrating direct oral anticoagulants into existing anticoagulation management services.克服将直接口服抗凝剂纳入现有抗凝管理服务的障碍。
Res Pract Thromb Haemost. 2018 Dec 12;3(1):136-137. doi: 10.1002/rth2.12171. eCollection 2019 Jan.