Facultie of Medicine, University of Helsinki, Helsinki, Finland.
Department of Otorhinolaryngology and Phoniatrics - Head and Neck Surgery, Helsinki University Hospital, Helsinki, Finland.
J Laryngol Otol. 2023 Apr;137(4):442-447. doi: 10.1017/S0022215122001165. Epub 2022 May 11.
Coronavirus disease 2019 has highlighted the lack of knowledge on aerosol exposure during respiratory activity and aerosol-generating procedures. This study sought to determine the aerosol concentrations generated by coughing to better understand, and to set a standard for studying, aerosols generated in medical procedures.
Aerosol exposure during coughing was measured in 37 healthy volunteers in the operating theatre with an optical particle sizer, from 40 cm, 70 cm and 100 cm distances.
Altogether, 306 volitional and 15 involuntary coughs were measured. No differences between groups were observed.
Many medical procedures are expected to generate aerosols; it is unclear whether they are higher risk than normal respiratory activity. The measured aerosol exposure can be used to determine the risk for significant aerosol generation during medical procedures. Considerable variation of aerosol generation during cough was observed between individuals, but whether cough was volitional or involuntary made no difference to aerosol production.
2019 年冠状病毒病凸显了人们对呼吸活动和产生气溶胶的操作过程中气溶胶暴露的了解不足。本研究旨在确定咳嗽产生的气溶胶浓度，以便更好地了解并为医学操作过程中产生的气溶胶制定标准。
在手术室中，使用光学粒子计数器对 37 名健康志愿者在 40cm、70cm 和 100cm 距离处咳嗽时的气溶胶暴露情况进行了测量。
共测量了 306 次自主咳嗽和 15 次非自主咳嗽，两组之间未观察到差异。
预计许多医疗程序都会产生气溶胶；目前尚不清楚它们比正常呼吸活动的风险更高。测量到的气溶胶暴露量可用于确定在医疗程序中产生大量气溶胶的风险。在个体之间观察到咳嗽时气溶胶产生的变化很大，但咳嗽是自主的还是非自主的对气溶胶的产生没有影响。
