Korea University Research Institute for Medical Bigdata Science, College of Medicine, Korea University, Seoul, Republic of Korea.
Department of Artificial Intelligence, Sejong University, Seoul, Republic of Korea.
Med Phys. 2022 Jul;49(7):4845-4860. doi: 10.1002/mp.15696. Epub 2022 May 27.
Although the surface registration technique has the advantage of being relatively safe and the operation time is short, it generally has the disadvantage of low accuracy.
This research proposes automated machine learning (AutoML)-based surface registration to improve the accuracy of image-guided surgical navigation systems.
The state-of-the-art surface registration concept is that first, using a neural network model, a new point-cloud that matches the facial information acquired by a passive probe of an optical tracking system (OTS) is extracted from the facial information obtained by computerized tomography. Target registration error (TRE) representing the accuracy of surface registration is then calculated by applying the iterative closest point (ICP) algorithm to the newly extracted point-cloud and OTS information. In this process, the hyperparameters used in the neural network model and ICP algorithm are automatically optimized using Bayesian optimization with expected improvement to yield improved registration accuracy.
Using the proposed surface registration methodology, the average TRE for the targets located in the sinus space and nasal cavity of the soft phantoms is 0.939 ± 0.375 mm, which shows 57.8% improvement compared to the average TRE of 2.227 ± 0.193 mm calculated by the conventional surface registration method (p < 0.01). The performance of the proposed methodology is evaluated, and the average TREs computed by the proposed methodology and the conventional method are 0.767 ± 0.132 and 2.615 ± 0.378 mm, respectively. Additionally, for one healthy adult, the clinical applicability of the AutoML-based surface registration is also presented.
Our findings showed that the registration accuracy could be improved while maintaining the advantages of the surface registration technique.
虽然表面配准技术具有相对安全和操作时间短的优点,但通常精度较低。
本研究提出了基于自动化机器学习(AutoML)的表面配准,以提高图像引导手术导航系统的准确性。
目前的表面配准概念是,首先使用神经网络模型,从计算机断层扫描(CT)获取的面部信息中提取与光学跟踪系统(OTS)被动探头获取的面部信息匹配的新点云。然后通过将新提取的点云和 OTS 信息应用迭代最近点(ICP)算法,计算代表表面配准精度的目标配准误差(TRE)。在这个过程中,使用贝叶斯优化和期望改进来自动优化神经网络模型和 ICP 算法中的超参数,以提高配准精度。
使用所提出的表面配准方法,在软体模型的窦腔和鼻腔中的目标的平均 TRE 为 0.939±0.375mm,与传统表面配准方法(p<0.01)计算的 2.227±0.193mm 的平均 TRE 相比,提高了 57.8%。评估了所提出的方法的性能,所提出的方法和传统方法计算的平均 TRE 分别为 0.767±0.132mm 和 2.615±0.378mm。此外,对于一名健康成年人,还展示了基于 AutoML 的表面配准的临床适用性。
我们的研究结果表明,在保持表面配准技术优势的同时,可以提高配准精度。