述评：阿杜卡奴单抗相关 ARIA：赞歌还是悲歌？

Commentary: Aducanumab-Related ARIA: Paean or Lament?

机构信息

From the Department of Radiology, Keck School of Medicine of USC, Los Angeles, CA.

出版信息

Clin Nucl Med. 2022 Aug 1;47(8):707-709. doi: 10.1097/RLU.0000000000004252. Epub 2022 May 11.

Abstract

Høilund-Carlsen and colleagues raise important issues related to amyloid PET, diagnosis of Alzheimer disease, and recently approved antiamyloid treatment aducanumab. We discuss new developments that may direct us to methods of presymptomatic detection of Alzheimer disease and development of effective prevention and therapy.

摘要

霍尔伦德-卡尔森（Høilund-Carlsen）及其同事提出了与淀粉样蛋白 PET、阿尔茨海默病诊断以及最近批准的抗淀粉样蛋白治疗药物 aducanumab 相关的重要问题。我们讨论了新的发展，这些发展可能会引导我们找到阿尔茨海默病的无症状检测方法，并开发有效的预防和治疗方法。