Department of Medicine, University of Ribeirão Preto, Brazil.
J Infect Dev Ctries. 2022 Apr 30;16(4):583-591. doi: 10.3855/jidc.14580.
Nonpharmaceutical Interventions (NPI) consist of compulsory (isolation, quarantine, stay-at-home orders, banning public gatherings, nonessential business closures, school closures), and voluntary (social distancing, handwashing, respiratory etiquette, and universal mask wearing) measures. The aim of this narrative review is to evaluate the different forms of NPI and their effectiveness in combating the pandemic. Isolation can be indicated for symptomatic and asymptomatic infected people at home or at hospitals depending on the patient's clinical picture. Quarantine is a social distancing intervention in asymptomatic uninfected people who had contact with SARS-CoV-2 infected individuals. Stay-at-home orders refer to statewide mandates imposing nonessential business closures, prohibition of public events and gatherings, and travel restrictions. Studies have suggested that stay-at-home orders may be associated with a reduction in the incidence of COVID-19 in some countries. Mask wearing decreases the risk of COVID-19 in the community, especially when the surgical masks are used for vulnerable people. N-95 respirators protect health workers from COVID-19. NPI may be helpful to curb the COVID-19 pandemic while mass vaccination worldwide is not attainable, and the threat of SARS-COV-2 variants remain on the horizon.
非药物干预(NPI)包括强制性(隔离、检疫、居家令、禁止公众集会、非必要商业关闭、学校关闭)和自愿性(社交距离、洗手、呼吸礼仪和普遍戴口罩)措施。本叙述性评论的目的是评估不同形式的 NPI 及其在对抗大流行中的有效性。隔离可根据患者的临床情况,在家中或医院对有症状和无症状感染者进行指示。检疫是对与 SARS-CoV-2 感染者有接触的无症状未感染者进行的社交距离干预措施。居家令是指在全州范围内实施非必要商业关闭、禁止公共活动和集会以及旅行限制的命令。研究表明,在一些国家,居家令可能与 COVID-19 发病率的降低有关。戴口罩可降低社区中 COVID-19 的风险,特别是在为弱势群体使用外科口罩时。N-95 呼吸器可保护医护人员免受 COVID-19 的侵害。在全球大规模接种疫苗不可行的情况下,NPI 可能有助于遏制 COVID-19 大流行,而 SARS-COV-2 变体的威胁仍在逼近。