Cardoso Fortunato José, Victor David Romeiro, Silva José Roberto da, Guimarães Angélica C, Leal Carla Adriane, Taveira Michelle Ribeiro, Alves João Guilherme
Departament of Hepatology, Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Pernambuco, Brazil.
Graduate Unit, Universidade de Pernambuco (UPE), Recife, Pernambuco, Brazil.
Sports Med Health Sci. 2023 Jul 27;5(3):174-180. doi: 10.1016/j.smhs.2023.07.010. eCollection 2023 Sep.
To verify systematically the association between the status of physical fitness and the risk of severe Coronavirus disease 2019 (COVID-19). This systematic review is in accordance with the Preferred Reporting Items for Systematic Review and Meta Analyses (PRISMA) statement and the eligibility criteria followed the Population, Intervention, Comparison, Outcomes and Study (PICOS) recommendation. PubMed, Embase, SciELO and Cochrane electronic databases were searched. All studies that explored the relationship between the pattern of physical fitness and COVID-19 adverse outcomes (hospitalization, intensive care unit admission, intubation, or mortality), were selected. The quality of the studies was assessed by the specific scale of the Newcastle-Ottawa Scale. A total of seven observational studies were identified in this systematic review; 13 468 patients were included in one case-control study, two cohort studies, and four cross-sectional studies. All studies reported an inverse association between high physical fitness and severe COVID-19 (hospitalization, intensive care admission, or mortality). Only some studies reported comorbidities, especially obesity and cardiovascular disorders, but the results remained unchanged after controlling for comorbidities. The quality of the seven studies included was moderate according to the Newcastle-Ottawa Quality Assessment Scale. The methodological heterogeneity of the studies included did not allow a meta-analysis of the findings. In conclusion, higher physical fitness levels were associated with lower risk of hospitalization, intensive care admissions, and mortality rates among patients with COVID-19.
为系统验证身体素质状况与2019年冠状病毒病（COVID-19）重症风险之间的关联。本系统评价遵循系统评价与Meta分析优先报告条目（PRISMA）声明，纳入标准遵循人群、干预措施、对照、结局和研究类型（PICOS）建议。检索了PubMed、Embase、SciELO和Cochrane电子数据库。纳入所有探讨身体素质模式与COVID-19不良结局（住院、重症监护病房收治、插管或死亡）之间关系的研究。采用纽卡斯尔-渥太华量表的特定量表评估研究质量。本系统评价共纳入7项观察性研究；1项病例对照研究、2项队列研究和4项横断面研究共纳入13468例患者。所有研究均报告身体素质良好与COVID-19重症（住院、重症监护病房收治或死亡）之间存在负相关。只有部分研究报告了合并症，尤其是肥胖和心血管疾病，但在控制合并症后结果未变。根据纽卡斯尔-渥太华质量评估量表，纳入的7项研究质量为中等。纳入研究的方法学异质性使得无法对研究结果进行Meta分析。总之，COVID-19患者身体素质水平较高与住院、重症监护病房收治风险及死亡率较低相关。
