Andersen T, Pedersen B H, Dissing I, Astrup A, Henriksen J H
Dept. of Internal Medicine, Hvidovre Hospital, University of Copenhagen, Denmark.
Scand J Gastroenterol. 1989 Mar;24(2):186-92. doi: 10.3109/00365528909093035.
Pouch volume, stoma diameter, and pouch emptying rate were measured postoperatively and after 6 months in 45 morbidly obese patients who had been assigned to either horizontal gastroplasty (HGP) or vertical banded gastroplasty (VBGP) after pretreatment with diet alone. Pouch volume and stoma diameter were measured by a standardized radiographic method with blinded assessment by two observers. Pouch emptying rate was determined by a standardized scintigraphic method and expressed as the mean transit time (t60). Pouch volume and stoma diameter did not change, whereas t60 decreased by 36% during the first 6 months after HGP (p less than 0.001). Pouch volume was larger after HGP (p less than 0.001). Pouch emptying was faster after VBGP (p less than 0.001), but these patients had the better weight loss (p less than 0.001). Variation in weight loss after either operation was unrelated to pouch volume, stoma diameter, and t60. Stoma diameter was not correlated with t60. The study provides further evidence against the significance of stoma diameter and pouch emptying rate as determinants of weight loss after gastroplasty. The much smaller pouch volume after VBGP may favor weight loss.
对45例病态肥胖患者在单纯饮食预处理后分别接受水平胃成形术（HGP）或垂直束带胃成形术（VBGP），术后及6个月后测量胃囊容积、造口直径和胃囊排空率。胃囊容积和造口直径采用标准化放射学方法测量，由两名观察者进行盲法评估。胃囊排空率通过标准化闪烁扫描法测定，并表示为平均通过时间（t60）。HGP术后最初6个月内，胃囊容积和造口直径未改变，而t60下降了36%（p<0.001）。HGP术后胃囊容积更大（p<0.001）。VBGP术后胃囊排空更快（p<0.001），但这些患者体重减轻更明显（p<0.001）。两种手术术后体重减轻的差异与胃囊容积、造口直径和t60无关。造口直径与t60不相关。该研究进一步证明胃成形术后造口直径和胃囊排空率作为体重减轻决定因素的意义不大。VBGP术后小得多的胃囊容积可能有利于体重减轻。
