Park Sangshin, Kim Min, Lee Dae In, Lee Ju-Hee, Kim Sangmin, Lee Sang Yeub, Bae Jang-Whan, Hwang Kyung-Kuk, Kim Dong-Woon, Cho Myeong-Chan, Bae Dae-Hwan
Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea.
Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Korea.
Acute Crit Care. 2024 Feb;39(1):194-198. doi: 10.4266/acc.2021.01158. Epub 2022 May 11.
The main mechanism of Takotsubo cardiomyopathy (TCM) is catecholamine-induced acute myocardial stunning. Pheochromocytoma, a catecholamine-secreting tumor, can cause several cardiovascular complications, including hypertensive crisis, myocardial infarction, toxic myocarditis, and TCM. A 29-year-old woman presented to our hospital with general weakness, vomiting, dyspnea, and chest pain. The patient was nullipara, 28 weeks' gestation, and had a cachexic morphology. Her cardiac enzyme levels were elevated and bedside echocardiography showed apical akinesia, suggesting TCM. The next day, she could not feel the fetal movement, and an emergency cesarean section was performed. After delivery, the patient experienced cardiac arrest and was transferred to the intensive care unit for cardiopulmonary resuscitation (CPR). Spontaneous circulation returned after 28 minutes of CPR, but cardiogenic shock continued, and extracorporeal membrane oxygenation (ECMO) was initiated. On the third day of ECMO maintenance, left ventricular ejection fraction improved and blood pressure stabilized. On the eighth day after ECMO insertion, it was removed. However, complications of the left leg vessels occurred, and several surgeries and interventions were performed. A left adrenal gland mass was found on computed tomography and was removed while repairing the leg vessels. Pheochromocytoma was diagnosed and left adrenalectomy was performed.
应激性心肌病(TCM)的主要机制是儿茶酚胺诱导的急性心肌顿抑。嗜铬细胞瘤是一种分泌儿茶酚胺的肿瘤,可导致多种心血管并发症,包括高血压危象、心肌梗死、中毒性心肌炎和应激性心肌病。一名29岁女性因全身乏力、呕吐、呼吸困难和胸痛就诊于我院。该患者未生育,妊娠28周,体型消瘦。她的心肌酶水平升高,床边超声心动图显示心尖运动减弱,提示应激性心肌病。第二天,她感觉不到胎动,遂行急诊剖宫产。分娩后,患者发生心脏骤停,被转至重症监护病房进行心肺复苏(CPR)。CPR 28分钟后恢复自主循环,但心源性休克持续存在,遂启动体外膜肺氧合(ECMO)。在维持ECMO的第三天,左心室射血分数改善,血压稳定。在插入ECMO后的第八天,将其撤除。然而,出现了左腿血管并发症,并进行了多次手术和干预。计算机断层扫描发现左侧肾上腺有肿块,在修复腿部血管时将其切除。诊断为嗜铬细胞瘤并进行了左侧肾上腺切除术。