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2020 年美国国立卫生研究院(NIH)资助的 COVID-19 研究:一项横断面研究。

NIH funding of COVID-19 research in 2020: a cross-sectional study.

机构信息

Department of Surgery, Johns Hopkins Medicine School of Medicine, Baltimore, Maryland, USA.

Department of Surgery, Johns Hopkins Medicine School of Medicine, Baltimore, Maryland, USA

出版信息

BMJ Open. 2022 May 11;12(5):e059041. doi: 10.1136/bmjopen-2021-059041.

DOI:10.1136/bmjopen-2021-059041
PMID:35545399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9096053/
Abstract

OBJECTIVE

This study aims to characterise and evaluate the National Institutes of Health's (NIH's) grant allocation speed and pattern of COVID-19 research.

DESIGN

Cross-sectional study.

SETTING

COVID-19 NIH RePORTER Dataset was used to identify COVID-19 relevant grants.

PARTICIPANTS

1108 grants allocated to COVID-19 research.

MAIN OUTCOMES AND MEASURES

The primary outcome was to determine the number of grants and funding amount the NIH allocated for COVID-19 by research type and clinical/scientific area. The secondary outcome was to calculate the time from the funding opportunity announcement to the award notice date.

RESULTS

The NIH awarded a total of 56 169 grants in 2020, of which 2.0% (n=1108) wwas allocated for COVID-19 research. The NIH had a US$45.3 billion budget that year, of which 4.9% (US$2.2 billion) was allocated to COVID-19 research. The most common clinical/scientific areas were social determinants of health (n=278, 8.5% of COVID-19 funding), immunology (n=211, 25.8%) and pharmaceutical interventions research (n=208, 47.6%). There were 104 grants studying COVID-19 non-pharmaceutical interventions, of which 2 grants studied the efficacy of face masks and 6 studied the efficacy of social distancing. Of the 83 COVID-19 funded grants on transmission, 5 were awarded to study airborne transmission of COVID-19 and 2 grants on transmission of COVID-19 in schools. The average time from the funding opportunity announcement to the award notice date was 151 days (SD: ±57.9).

CONCLUSION

In the first year of the pandemic, the NIH diverted a small fraction of its budget to COVID-19 research. Future health emergencies will require research funding to pivot in a timely fashion and funding levels to be proportional to the anticipated burden of disease in the population.

摘要

目的

本研究旨在描述和评估美国国立卫生研究院(NIH)在 COVID-19 研究方面的拨款速度和模式。

设计

横断面研究。

设置

使用 COVID-19 NIH RePORTER 数据集来确定与 COVID-19 相关的拨款。

参与者

分配给 COVID-19 研究的 1108 项拨款。

主要结果和测量

主要结果是确定 NIH 按研究类型和临床/科学领域为 COVID-19 分配的拨款数量和资金额。次要结果是计算从拨款机会公告到授予通知日期的时间。

结果

NIH 在 2020 年共授予了 56169 项拨款,其中 2.0%(n=1108)用于 COVID-19 研究。NIH 当年的预算为 453 亿美元,其中 4.9%(42 亿美元)用于 COVID-19 研究。最常见的临床/科学领域是健康的社会决定因素(n=278,占 COVID-19 资金的 8.5%)、免疫学(n=211,25.8%)和药物干预研究(n=208,47.6%)。有 104 项研究 COVID-19 非药物干预措施的拨款,其中 2 项研究口罩的功效,6 项研究社会隔离的功效。在 83 项关于传播的 COVID-19 资助拨款中,有 5 项授予研究 COVID-19 的空气传播,2 项授予研究 COVID-19 在学校的传播。从拨款机会公告到授予通知日期的平均时间为 151 天(SD:±57.9)。

结论

在大流行的第一年,NIH 将其预算的一小部分用于 COVID-19 研究。未来的卫生紧急情况将需要研究资金及时转向,并且资金水平与预期人群疾病负担成正比。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e125/9096053/cafc62072ce4/bmjopen-2021-059041f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e125/9096053/240f9864f94b/bmjopen-2021-059041f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e125/9096053/cafc62072ce4/bmjopen-2021-059041f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e125/9096053/240f9864f94b/bmjopen-2021-059041f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e125/9096053/cafc62072ce4/bmjopen-2021-059041f02.jpg

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NIH disease funding levels and burden of disease.NIH 疾病资助水平与疾病负担。
PLoS One. 2011 Feb 24;6(2):e16837. doi: 10.1371/journal.pone.0016837.
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The relation between funding by the National Institutes of Health and the burden of disease.美国国立卫生研究院的资金投入与疾病负担之间的关系。
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