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表现为头皮肿块的外周T细胞淋巴瘤

Peripheral T-Cell Lymphoma Presenting as a Scalp Mass.

作者信息

Kim Moo Seong, Pyo Se Young, Park Ha Young, Jo Hyuck Rae, Kim Jeongeun

机构信息

Department of Neurosurgery, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

Department of Anatomic Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

出版信息

Brain Tumor Res Treat. 2022 Apr;10(2):113-116. doi: 10.14791/btrt.2022.0004.

DOI:10.14791/btrt.2022.0004
PMID:35545831
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9098978/
Abstract

Peripheral scalp T-cell lymphoma is a very rare disease. We report a case of a 22-year-old man who presented an indolent large scalp mass in the right frontal scalp region. The patient's physical examination demonstrated no palpable mass in the chest, abdomen, and extremities. The brain CT revealed a high-density large scalp mass of the subgaleal layer in the right frontal and a small scalp mass of the subgaleal layer in the left frontal. The brain MRI showed multifocal enhancing masses in the bilateral dura, the subgaleal layer of the scalp, and the skull. The patient underwent removal of the tumor found in the right frontal scalp. The histologic diagnosis was peripheral T-cell lymphoma. Bone marrow aspiration showed the involvement of T-cell lymphoma. The patient received chemotherapy with cyclophosphamide, vincristine, doxorubicin, and prednisolone (CHOP protocol) for 3 cycles. The patient was discharged without neurological deficit. The patient showed no evidence of recurrence 15 months after surgery. We report a rare case of peripheral T-cell lymphoma mimicking benign scalp tumors.

摘要

外周头皮T细胞淋巴瘤是一种非常罕见的疾病。我们报告一例22岁男性病例,其右额部头皮区域出现一个惰性大头皮肿块。患者体格检查显示胸部、腹部和四肢未触及肿块。脑部CT显示右额部帽状腱膜下层有一个高密度大头皮肿块,左额部帽状腱膜下层有一个小头皮肿块。脑部MRI显示双侧硬脑膜、头皮帽状腱膜下层和颅骨有多灶性强化肿块。患者接受了右额部头皮肿瘤切除术。组织学诊断为外周T细胞淋巴瘤。骨髓穿刺显示T细胞淋巴瘤受累。患者接受了环磷酰胺、长春新碱、阿霉素和泼尼松龙(CHOP方案)化疗3个周期。患者出院时无神经功能缺损。术后15个月患者无复发迹象。我们报告一例罕见的外周T细胞淋巴瘤,其表现类似良性头皮肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/7648e5846975/btrt-10-113-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/1ee06160b662/btrt-10-113-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/212c487d9479/btrt-10-113-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/d89b796e9e04/btrt-10-113-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/7648e5846975/btrt-10-113-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/1ee06160b662/btrt-10-113-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/212c487d9479/btrt-10-113-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/d89b796e9e04/btrt-10-113-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e10/9098978/7648e5846975/btrt-10-113-g004.jpg

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Aggressive CD4-CD8-CD45RA+CCR10- Primary Cutaneous Peripheral T-cell Lymphoma, Not Otherwise Specified: A Case Report.侵袭性CD4-CD8-CD45RA+CCR10-原发性皮肤外周T细胞淋巴瘤,非特殊类型:一例报告
Acta Derm Venereol. 2019 Nov 1;99(12):1176-1177. doi: 10.2340/00015555-3310.
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Primary CNS lymphoma other than DLBCL: a descriptive analysis of clinical features and treatment outcomes.
原发性中枢神经系统淋巴瘤非弥漫性大 B 细胞淋巴瘤:临床特征和治疗结果的描述性分析。
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