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A comment on metformin and COVID-19 with regard to "Metformin use is associated with a decrease in the risk of hospitalization and mortality in COVID-19 patients with diabetes: A population-based study in Lombardy".关于“二甲双胍的使用与糖尿病COVID-19患者住院风险和死亡率的降低相关：伦巴第地区的一项基于人群的研究”的对二甲双胍与COVID-19的评论
Diabetes Obes Metab. 2022 Sep;24(9):1888-1893. doi: 10.1111/dom.14746. Epub 2022 May 25.
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Effects of metformin, insulin on COVID-19 patients with pre-existed type 2 diabetes: A multicentral retrospective study.二甲双胍和胰岛素对合并 2 型糖尿病的 COVID-19 患者的影响：一项多中心回顾性研究。
Life Sci. 2021 Jun 15;275:119371. doi: 10.1016/j.lfs.2021.119371. Epub 2021 Mar 19.
4
Metformin use before COVID-19 vaccination and the risks of COVID-19 incidence, medical utilization, and all-cause mortality in patients with type 2 diabetes mellitus.二甲双胍在 COVID-19 疫苗接种前的使用与 2 型糖尿病患者 COVID-19 发病率、医疗利用和全因死亡率的风险。
Diabetes Res Clin Pract. 2023 Jun;200:110692. doi: 10.1016/j.diabres.2023.110692. Epub 2023 May 6.
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Inpatient use of metformin and acarbose is associated with reduced mortality of COVID-19 patients with type 2 diabetes mellitus.住院使用二甲双胍和阿卡波糖与降低 2 型糖尿病 COVID-19 患者的死亡率相关。
Endocrinol Diabetes Metab. 2022 Jan;5(1):e00301. doi: 10.1002/edm2.301. Epub 2021 Sep 29.
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Metformin is associated with lower hospitalizations, mortality and severe coronavirus infection among elderly medicare minority patients in 8 states in USA.在美国8个州的老年医疗保险少数族裔患者中，二甲双胍与较低的住院率、死亡率和严重冠状病毒感染相关。
Diabetes Metab Syndr. 2021 Mar-Apr;15(2):513-518. doi: 10.1016/j.dsx.2021.02.022. Epub 2021 Feb 18.
7
Risk of Metformin in Patients With Type 2 Diabetes With COVID-19: A Preliminary Retrospective Report.COVID-19 合并 2 型糖尿病患者使用二甲双胍的风险：初步回顾性报告。
Clin Transl Sci. 2020 Nov;13(6):1055-1059. doi: 10.1111/cts.12897. Epub 2020 Oct 19.
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Metformin use is associated with a decrease in the risk of hospitalization and mortality in COVID-19 patients with diabetes: A population-based study in Lombardy.二甲双胍的使用与 COVID-19 合并糖尿病患者住院和死亡风险的降低相关：伦巴第地区的一项基于人群的研究。
Diabetes Obes Metab. 2022 May;24(5):891-898. doi: 10.1111/dom.14648. Epub 2022 Jan 25.
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Is metformin a miracle or a menace in COVID-19 patients with type 2 diabetes?二甲双胍在 2 型糖尿病合并 COVID-19 患者中是“灵丹妙药”还是“洪水猛兽”？
J Diabetes Investig. 2021 Apr;12(4):479-481. doi: 10.1111/jdi.13484. Epub 2021 Jan 18.
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Metformin Use in Diabetes Prior to Hospitalization: Effects on Mortality in Covid-19.住院前糖尿病患者使用二甲双胍：对2019冠状病毒病死亡率的影响
Endocr Pract. 2020 Oct;26(10):1166-1172. doi: 10.4158/EP-2020-0466.

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Effects of Metformin Delivery via Biomaterials on Bone and Dental Tissue Engineering.生物材料递送二甲双胍对骨和牙齿组织工程的影响。
Int J Mol Sci. 2022 Dec 14;23(24):15905. doi: 10.3390/ijms232415905.

本文引用的文献

1
Metformin use is associated with a decrease in the risk of hospitalization and mortality in COVID-19 patients with diabetes: A population-based study in Lombardy.二甲双胍的使用与 COVID-19 合并糖尿病患者住院和死亡风险的降低相关：伦巴第地区的一项基于人群的研究。
Diabetes Obes Metab. 2022 May;24(5):891-898. doi: 10.1111/dom.14648. Epub 2022 Jan 25.
2
Prior Glucose-Lowering Medication Use and 30-Day Outcomes Among 64,892 Veterans With Diabetes and COVID-19.有 COVID-19 病史的 64892 例糖尿病退伍军人的降糖药物使用史与 30 天结局。
Diabetes Care. 2021 Dec;44(12):2708-2713. doi: 10.2337/dc21-1351. Epub 2021 Oct 6.
3
Prescription of glucose-lowering therapies and risk of COVID-19 mortality in people with type 2 diabetes: a nationwide observational study in England.降糖治疗处方与 2 型糖尿病患者 COVID-19 死亡率的关系：英国全国性观察研究。
Lancet Diabetes Endocrinol. 2021 May;9(5):293-303. doi: 10.1016/S2213-8587(21)00050-4. Epub 2021 Mar 30.
4
Metformin is associated with lower hospitalizations, mortality and severe coronavirus infection among elderly medicare minority patients in 8 states in USA.在美国8个州的老年医疗保险少数族裔患者中，二甲双胍与较低的住院率、死亡率和严重冠状病毒感染相关。
Diabetes Metab Syndr. 2021 Mar-Apr;15(2):513-518. doi: 10.1016/j.dsx.2021.02.022. Epub 2021 Feb 18.
5
Outpatient metformin use is associated with reduced severity of COVID-19 disease in adults with overweight or obesity.门诊使用二甲双胍与超重或肥胖的成年人 COVID-19 疾病严重程度降低相关。
J Med Virol. 2021 Jul;93(7):4273-4279. doi: 10.1002/jmv.26873. Epub 2021 Mar 23.
6
[Can diabetes and its related hypoglycemic drug treatment be considered risk factors for health outcomes in COVID-19 patients? The results of a study in the population residing in Sicily Region (Southern Italy)].糖尿病及其相关降糖药物治疗能否被视为新冠病毒肺炎患者健康结局的危险因素？一项针对意大利南部西西里岛地区居民的研究结果
Epidemiol Prev. 2020 Sep-Dec;44(5-6 Suppl 2):315-322. doi: 10.19191/EP20.5-6.S2.132.

A comment on metformin and COVID-19 with regard to "Metformin use is associated with a decrease in the risk of hospitalization and mortality in COVID-19 patients with diabetes: A population-based study in Lombardy".

作者信息

Al-Salameh Abdallah, Wiernsperger Nicolas, Cariou Bertrand, Lalau Jean-Daniel

机构信息

Department of Endocrinology-Diabetes Mellitus and Nutrition, Amiens University Hospital, Amiens, France.

PériTox, UMR-I 01, University of Picardie Jules Verne, Amiens, France.

出版信息

Diabetes Obes Metab. 2022 Sep;24(9):1888-1893. doi: 10.1111/dom.14746. Epub 2022 May 25.

DOI:10.1111/dom.14746
PMID:35545864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9348286/
Abstract
摘要