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英国注射毒品人群特征:1980-2019 年年龄、持续时间和注射发生率的变化,利用重复横断面调查的证据。

The characteristics of people who inject drugs in the United Kingdom: changes in age, duration, and incidence of injecting, 1980-2019, using evidence from repeated cross-sectional surveys.

机构信息

Public Health and Clinical Directorate, UK Health Security Agency, London, UK.

Department of Epidemiology and Public Health, University College London, London, UK.

出版信息

Addiction. 2022 Sep;117(9):2471-2480. doi: 10.1111/add.15911. Epub 2022 May 12.

Abstract

BACKGROUND AND AIMS

Mortality and drug treatment data suggest that the median age of people who inject drugs is increasing. We aimed to describe changes in the characteristics of people injecting drugs in the United Kingdom (UK).

DESIGN

Repeat cross-sectional surveys and modelling.

SETTING

Low-threshold services in the United Kingdom such as needle and syringe programmes.

PARTICIPANTS

A total of 79 900 people who recently injected psychoactive drugs in the United Kingdom, recruited as part of the Unlinked Anonymous Monitoring Survey (England, Wales, Northern Ireland, 1990-2019) and Needle Exchange Surveillance Initiative (Scotland, 2008-2019).

MEASUREMENTS

Age of people currently injecting, age at first injection, duration of injecting (each 1990-2019) and estimates of new people who started injecting (1980-2019).

FINDINGS

In England, Wales and Northern Ireland between 1990 and 2019, the median age of people injecting increased from 27 (interquartile range [IQR], 24-31) to 40 (IQR, 34-46); median age at first injection increased from 22 (IQR, 19-25) to 33 (IQR, 28-39); and median years of injecting increased from 7 (IQR, 3-11) to 18 (IQR, 9-23). Values in Scotland and England were similar after 2008. The estimated number that started injecting annually in England increased from 5470 (95% prediction interval [PrI] 3120-6940) in 1980 to a peak of 10 270 (95% PrI, 8980-12 780) in 1998, and then decreased to 2420 (95% PrI, 1320-5580) in 2019. The number in Scotland followed a similar pattern, increasing from 1220 (95% PrI, 740-2430) in 1980 to a peak of 3080 (95% PrI, 2160-3350) in 1998, then decreased to a 270 (95% PrI, 130-600) in 2018. The timing of the peak differed between regions, with earlier peaks in London and the North West of England.

CONCLUSIONS

In the United Kingdom, large cohorts started injecting psychoactive drugs in the 1980s and 1990s and many still inject today. Relatively few people started in more recent years. This has led to changes in the population injecting drugs, including an older average age and longer injecting histories.

摘要

背景和目的

死亡率和药物治疗数据表明,注射毒品者的中位数年龄正在增加。我们旨在描述英国(英国)注射毒品者特征的变化。

设计

重复的横断面调查和建模。

地点

英国的低门槛服务,如针具和注射器计划。

参与者

共有 79900 名最近在英国注射过精神活性药物的人,作为匿名监测调查(英格兰、威尔士、北爱尔兰,1990-2019 年)和针具交换监测计划(苏格兰,2008-2019 年)的一部分被招募。

测量

目前注射毒品者的年龄、首次注射年龄、注射时间(每 1990-2019 年)和估计的新注射毒品者人数(1980-2019 年)。

结果

在英格兰、威尔士和北爱尔兰,1990 年至 2019 年间,注射毒品者的中位年龄从 27 岁(四分位距[IQR],24-31 岁)增加到 40 岁(IQR,34-46 岁);首次注射年龄中位数从 22 岁(IQR,19-25 岁)增加到 33 岁(IQR,28-39 岁);注射年限中位数从 7 岁(IQR,3-11 岁)增加到 18 岁(IQR,9-23 岁)。苏格兰的数值在 2008 年后类似。1980 年,英国每年开始注射的人数估计为 5470 人(95%预测区间[PrI]3120-6940),1998 年达到峰值 10270 人(95%PrI8980-12270),然后下降到 2019 年的 2420 人(95%PrI1320-5580)。苏格兰的数字也呈现出类似的模式,从 1980 年的 1220 人(95%PrI740-2430)增加到 1998 年的峰值 3080 人(95%PrI2160-3350),然后下降到 2018 年的 270 人(95%PrI130-600)。不同地区的高峰期时间不同,伦敦和英格兰西北部的高峰期更早。

结论

在英国,大量人群在 20 世纪 80 年代和 90 年代开始注射精神活性药物,而今天仍有许多人在注射。近年来,相对较少的人开始注射。这导致了注射毒品人群的变化,包括平均年龄的增加和更长的注射史。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79aa/9544601/a5ec484c3fc2/ADD-117-2471-g003.jpg

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