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比较特发性羊水过多孕妇的妊娠、分娩和新生儿结局:一项前瞻性队列研究。

Comparing pregnancy, childbirth, and neonatal outcomes in women with idiopathic polyhydramnios: a prospective cohort study.

机构信息

Department of Gynecology and Obstetrics, Yasuj University of Medical Sciences, Yasuj, Iran.

Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.

出版信息

BMC Pregnancy Childbirth. 2022 May 11;22(1):399. doi: 10.1186/s12884-022-04625-y.

Abstract

BACKGROUND

In this prospective cohort study, the perinatal outcome in idiopathic polyhydramnios compared with normal pregnancies was examined.

METHODS

This was a prospective cohort study of 180 singleton pregnancies who received care at the referral gynecology clinic of Yasuj, Iran between 2018-2020. The inclusion criteria comprised singleton pregnancies, gestational age > 34 weeks; fetuses without structural and chromosomal abnormalities in pregnancy screening test, no maternal diabetes, negative TORCH negative screening test, no Rh factor isoimmunization. Polyhydramnios was defined as: (i) amniotic fluid index ≥ 24 cm; (ii) maximal vertical pocket of ≥ 8 cm. Perinatal outcomes were recorded in both groups.

RESULTS

Postpartum hemorrhage (7.8% vs. 2.2; OR: 1.60; 95% CI 1.09-2.34) and cesarean delivery (51.11% vs. 21.11; OR: 1.88; 95% CI 1.42-2.50) and respiratory distress (4.4 v vs. 0; OR: 2.04; 95 C CI 1.75-2.80) was significantly higher in the idiopathic polyhydramnios (P ≤ 0.05) compared to normal pregnancy, which increased with severity of idiopathic polyhydramnios.

CONCLUSION

In conclusion, the results of the current study, suggest that idiopathic polyhydramnios may be associated with a higher rate of postpartum hemorrhage, cesarean delivery, and respiratory distress than a normal pregnancy.

摘要

背景

在这项前瞻性队列研究中,我们检查了特发性羊水过多与正常妊娠的围产结局。

方法

这是一项前瞻性队列研究,纳入了 2018 年至 2020 年期间在伊朗亚苏季转诊妇科诊所就诊的 180 例单胎妊娠。纳入标准包括:单胎妊娠、妊娠周数>34 周;妊娠筛查试验中胎儿无结构和染色体异常、无母体糖尿病、TORCH 阴性筛查试验阴性、无 Rh 因子同种免疫。羊水过多的定义为:(i)羊水指数≥24cm;(ii)最大垂直羊水深度≥8cm。在两组中记录围产结局。

结果

产后出血(7.8% vs. 2.2%;OR:1.60;95%CI 1.09-2.34)、剖宫产(51.11% vs. 21.11%;OR:1.88;95%CI 1.42-2.50)和呼吸窘迫(4.4% vs. 0%;OR:2.04;95%CI 1.75-2.80)在特发性羊水过多组显著高于正常妊娠组(P≤0.05),且随着特发性羊水过多的严重程度增加而增加。

结论

总之,本研究结果表明,与正常妊娠相比,特发性羊水过多可能与更高的产后出血、剖宫产和呼吸窘迫发生率相关。

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