Department of Pediatrics, Affiliated Hospital of Yanbian University, Jilin, China.
Health Management Center, Children's Hospital of Changchun City, Jilin, China.
J Coll Physicians Surg Pak. 2022 May;32(5):602-605. doi: 10.29271/jcpsp.2022.05.602.
To investigate the predictive value of neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in premature rupture of membranes complicated by sepsis.
A descriptive study.
Department of Paediatrics, Affiliated Hospital of Yanbian University, China, from January 2020 to June 2021.
Ninety-nine children with premature rupture of membranes and sepsis were included as group A and 99 children without sepsis were included as group B. Logistic regression analysis was used to analyse the risk factors for premature rupture of membranes complicated by sepsis. The diagnostic value of PLR and NLR in sepsis complicated by premature rupture of membranes was assessed by subject operating characteristic curve (ROC) curves.
Univariate analysis showed significant differences between groups A and B in terms of mode of delivery, lymphocyte count, platelets, PLR and NLR (p <0.05). Logistic regression analysis showed that mode of delivery, platelets, PLR and NLR were independent risk factors for premature rupture of membranes complicated by sepsis (p <0.05). The ROC area for PLR was 0.781 (95% CI: 0.718-0.844, p <0.001), which was greater than that for NLR when premature rupture of membranes complicated by sepsis was predicted. When the PLR was >93.072, the sensitivity of predicting premature rupture of membranes complicated by sepsis was 67.7% and the specificity was 79.8%.
PLR and NLR have a high predictive value for premature rupture of membranes complicated by sepsis. Among them, the predictive value of PLR was greater than NLR.
Premature rupture of membranes, Sepsis, PLR, NLR, Subject operating characteristic curve (ROC).
探讨中性粒细胞/淋巴细胞比值（NLR）和血小板/淋巴细胞比值（PLR）对胎膜早破并发脓毒症的预测价值。
描述性研究。
中国延边大学附属医院儿科，2020 年 1 月至 2021 年 6 月。
纳入 99 例胎膜早破合并脓毒症患儿为 A 组，99 例无脓毒症患儿为 B 组。采用 logistic 回归分析胎膜早破并发脓毒症的危险因素。采用受试者工作特征曲线（ROC）评估 PLR 和 NLR 对胎膜早破并发脓毒症的诊断价值。
单因素分析显示，A 组与 B 组在分娩方式、淋巴细胞计数、血小板、PLR 和 NLR 方面存在显著差异（p<0.05）。logistic 回归分析显示，分娩方式、血小板、PLR 和 NLR 是胎膜早破并发脓毒症的独立危险因素（p<0.05）。PLR 的 ROC 曲线下面积为 0.781（95%CI：0.718-0.844，p<0.001），预测胎膜早破并发脓毒症时大于 NLR。当 PLR>93.072 时，预测胎膜早破并发脓毒症的敏感性为 67.7%，特异性为 79.8%。
PLR 和 NLR 对胎膜早破并发脓毒症具有较高的预测价值。其中，PLR 的预测价值大于 NLR。
胎膜早破、脓毒症、PLR、NLR、受试者工作特征曲线（ROC）。
