Outcomes of Cardiopulmonary Resuscitation of Oncologic Patients in Emergency Department.

OBJECTIVE

To evaluate the outcomes of cardiopulmonary resuscitation (CPR) of oncological cases versus non-oncological admitted to the emergency department as out-of-hospital cardiac arrest (OHCA) or in-hospital cardiac arrest (IHCA).

STUDY DESIGN

Descriptive study.

PLACE AND DURATION OF STUDY

Emergency Department (ED) of Eskisehir Osmangazi University Hospital, between January 2014 to January 2020.

METHODOLOGY

Victims over the age of 18 years who had OHCA and IHCA were inducted. The outcomes of 109 patients with an oncological diagnosis and 109 controls without cancer underwent CPR and were compared.

RESULTS

The median age of the participants was 65 (58-76) years. Patients with an oncological diagnosis were more likely to have an IHCA [OR: 2.98 (95% CI: 1.68-5.30), p <0.001]. The IHCA and OHCA rates of patients without an oncological diagnosis were similar. Solid-organ malignancies were observed in 102 patients (93.6%). The initial rhythm of 88 patients (80.7%) in the oncological arrest group was asystole versus 77 patients (70.6%) in the control group. Pulseless electrical activity was observed in 17 patients (15.6%) in the study group and in 24 patients (22.0%) in the control group. Although the non-oncological group was found to have a longer stay. No statistically significant difference was found between the study and control groups regarding duration of stay in the intensive care unit. Only one patient (2.0%) with cancer was discharged in stable state as against 10 (21.3%) of non-oncological arrests [OR: 12.97 (95% CI: 1.59-105.93), p = 0.008].

CONCLUSION

The presence of cancer is not a favourable prognostic factor for the success of CPR.

KEY WORDS

Oncology, Cardiac arrest, IHCA, OHCA, Emergency department.