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新分离的GXU-A23菌株可改善幼鱼的生长性能、抗氧化和抗炎状态、代谢能力及中肠形态。

A Newly Isolated Strain of GXU-A23 Improves the Growth Performance, Antioxidant and Anti-Inflammatory Status, Metabolic Capacity and Mid-intestine Morphology of Juvenile .

作者信息

Fang HaoHang, Zhuang ZhenXiao, Huang LuoDong, Niu Jin, Zhao Wei

机构信息

College of Life Sciences, Sun Yat-sen University, Guangzhou, China.

Institute of Marine Research, Bergen, Norway.

出版信息

Front Physiol. 2022 Apr 25;13:882091. doi: 10.3389/fphys.2022.882091. eCollection 2022.

Abstract

can be used as a green additive in aquafeeds due to it contains rich astaxanthin and polyunsaturated fatty acid. In the present study, a newly strain of GXU-A23 with high concentration of astaxanthin was firstly isolated by a newly culture strategy in our laboratory. In addition, GXU-A23 was applied in the feed for determining whether it has positive effects on the growth performance, antioxidant and anti-inflammatory status, metabolic capacity and mid-intestine morphology of juvenile . Shrimp with 0.63 g approximately initial body weight were fed diets supplemented with/without 50 g/kg GXU-A23. After 8 weeks feeding intervention, significantly higher growth performance of was obtained in the GXU-A23 treatment group compared to the control group ( < 0.05). At the same time, fed with GXU-A23 acquired significantly better antioxidant and anti-inflammatory status than the control group ( < 0.05). In addition, higher RNA expression level of hepatopancreas digestive enzyme, hepatopancreas lipid and glucose metabolic enzymes as well as better mid-intestine morphology were found in the GXU-A23 treatment group than the control group ( < 0.05). These results indicated that 50 g/kg GXU-A23 was suitable for the feed, which could improve the growth performance, antioxidant and anti-inflammatory status, metabolic capacity and mid-intestine morphology of juvenile

摘要

由于其富含虾青素和多不饱和脂肪酸,可作为水产饲料中的绿色添加剂。在本研究中,本实验室采用一种新的培养策略首次分离出了一株虾青素含量高的新菌株GXU - A23。此外,将GXU - A23应用于饲料中,以确定其对幼虾的生长性能、抗氧化和抗炎状态、代谢能力以及中肠形态是否有积极影响。将初始体重约0.63克的虾投喂添加/不添加50克/千克GXU - A23的饲料。经过8周的投喂干预,与对照组相比,GXU - A23处理组的虾生长性能显著更高(P<0.05)。同时,投喂GXU - A23的虾获得的抗氧化和抗炎状态明显优于对照组(P<0.05)。此外,GXU - A23处理组的肝胰腺消化酶、肝胰腺脂质和葡萄糖代谢酶的RNA表达水平更高,中肠形态也比对照组更好(P<0.05)。这些结果表明,50克/千克的GXU - A23适用于虾饲料,可提高幼虾的生长性能、抗氧化和抗炎状态、代谢能力以及中肠形态

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