Redman C W
Am J Kidney Dis. 1987 Apr;9(4):324-7. doi: 10.1016/s0272-6386(87)80130-0.
The poor perinatal outcome of pregnant women with chronic hypertension depends on their increased susceptibility to superimposed preeclampsia. There is no direct evidence that this is mediated by hypertension and reduced by antihypertensive treatment. In particular, the arterial lesions of the uteroplacental circulation in preeclampsia also occur in normotensive individuals and would be unusual types of pressure-induced injury. Thus, there is no compelling reason for treating hypertension below a threshold (170/110 mm Hg) above which maternal safety becomes the main concern.
慢性高血压孕妇围产期结局不佳取决于其并发子痫前期易感性增加。尚无直接证据表明这是由高血压介导且可通过降压治疗减轻。特别是，子痫前期子宫胎盘循环的动脉病变在血压正常的个体中也会出现，且属于异常类型的压力性损伤。因此，没有令人信服的理由在阈值（170/110 mmHg）以下治疗高血压，高于该阈值时，母亲安全成为主要关注点。
