Grant Jon E, Chamberlain Samuel R
Department of Psychiatry & Behavioral Neuroscience, University of Chicago, USA.
Department of Psychiatry, Faculty of Medicine, University of Southampton, UK; Southern Health NHS Foundation Trust, Southampton, UK.
J Psychiatr Res. 2022 Jul;151:365-367. doi: 10.1016/j.jpsychires.2022.05.001. Epub 2022 May 5.
Trichotillomania (TTM) and skin picking disorder (SPD) have been characterized as body-focused repetitive behaviors (BFRBs) and have been grouped in the DSM-5 as part of the obsessive-compulsive and related disorders. Despite the clinical similarities between BFRBs and the compulsions of OCD, there has been little research regarding the degree to which compulsivity underpins these behaviors. 88 adults (69 female; mean age 30.9 years) with DSM-5 TTM or SPD completed standard diagnostic interviews, basic demographic information, symptom inventories about TTM and SPD, and measures of disability/functioning. Compulsivity was measured using the 15-item Cambridge-Chicago Compulsivity Trait Scale (CHI-T). Relationships between CHI-T scores and the other measures of interest were characterized using Pearson's correlations. Of the 88 participants, 48 (54.5%) had TTM, 37 (42.0%) had SPD and 3 (3.4%) had both. CHI-T total scores correlated with worse disability and quality of life but not with BFRB symptom severity. This study demonstrates that compulsivity is a marked contributor to worse disability and quality of life in people with BFRBs, more so than conventional measures of BFRB symptom severity (which did not correlate with disability/quality of life). Future work should include compulsivity measures in BFRB studies (including treatment trials) and explore its role in other related disorders.
拔毛癖(TTM)和皮肤搔抓障碍(SPD)已被归类为躯体聚焦重复行为(BFRB),并在《精神疾病诊断与统计手册》第5版(DSM-5)中被归为强迫症及相关障碍的一部分。尽管BFRB与强迫症的强迫行为在临床上有相似之处,但关于强迫性在多大程度上支撑这些行为的研究却很少。88名患有DSM-5定义的TTM或SPD的成年人(69名女性;平均年龄30.9岁)完成了标准诊断访谈、基本人口统计学信息、关于TTM和SPD的症状清单以及残疾/功能测量。使用15项剑桥-芝加哥强迫特质量表(CHI-T)测量强迫性。使用Pearson相关性分析来描述CHI-T分数与其他相关测量之间的关系。在88名参与者中,48名(54.5%)患有TTM,37名(42.0%)患有SPD,3名(3.4%)同时患有这两种疾病。CHI-T总分与更严重的残疾和生活质量相关,但与BFRB症状严重程度无关。这项研究表明,强迫性是导致BFRB患者残疾加重和生活质量下降的一个显著因素,比传统的BFRB症状严重程度测量指标(与残疾/生活质量无关)的影响更大。未来的研究工作应在BFRB研究(包括治疗试验)中纳入强迫性测量,并探索其在其他相关障碍中的作用。