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[头孢氨苄和红霉素连续及分次口服给药时代表性肠道微生物的黏附能力]

[The adhesive capacity of representative intestinal microflora in the continuous and split oral administration of cephalexin and erythromycin].

作者信息

Gorskaia E M, Lapchinskaia A V, Chakhava O V, Shenderov B A, Trapezov E V

出版信息

Antibiot Med Biotekhnol. 1987 Mar;32(3):210-3.

PMID:3555328
Abstract

When cephalexin and erythromycin were administered intragastrically with intervals, adhesion of facultative pathogenic bacteria such as Klebsiella, Staphylococcus and E. coli to enterocytes of the small intestine in vitro was more pronounced than with their continuous administration with drinking water. The adhesive capacity of the staphylococcal strains resistant to the antibiotics was higher than that of the sensitive ones.

摘要

当头孢氨苄和红霉素间隔灌胃给药时,体外培养条件下,克雷伯菌、葡萄球菌和大肠杆菌等兼性致病菌对小肠肠上皮细胞的黏附作用,比它们与饮用水连续给药时更为明显。对抗生素耐药的葡萄球菌菌株的黏附能力高于敏感菌株。

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