Ono Toshikazu, Xu Ning, Koga Daiki, Ideo Toshihiro, Sugimoto Manabu, Hisaeda Yoshio
Department of Chemistry and Biochemistry, Graduate School of Engineering, Center for Molecular Systems (CMS), Kyushu University Fukuoka 819-0395 Japan
PRESTO, Japan Science and Technology Agency (JST) 4-1-8 Honcho Kawaguchi Saitama 332-0012 Japan.
RSC Adv. 2018 Nov 26;8(69):39269-39273. doi: 10.1039/c8ra09040h. eCollection 2018 Nov 23.
The gram-scale production of porphycene derivatives is reported. This has been achieved by acid-catalyzed ring closure of an /-mixture of 5,6-diaryldipyrroethenes, resulting in the formation of -tetraarylporphycenes in yields of up to 80%. /-isomerization of the 5,6-diaryldipyrroethenes under acidic conditions was key to proceed the effective macrocyclization.
报道了卟吩衍生物的克级规模制备。这是通过酸催化5,6-二芳基二吡咯乙烯的/-混合物闭环反应实现的，生成-四芳基卟吩的产率高达80%。5,6-二芳基二吡咯乙烯在酸性条件下的/-异构化是有效进行大环化反应的关键。
