Guo Fuyou, Turgut Mehmet
Department of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Henan International Joint Laboratory of Nervous System Malformation, Zhengzhou, China.
Front Surg. 2022 Mar 28;9:850879. doi: 10.3389/fsurg.2022.850879. eCollection 2022.
Diagnosis of Chirai malformation type I (CM-I) is based on magnetic resonance imaging of the brain or cervical spinal cord. The main goal of surgery is to relieve the blockage to the free pulsatile flow of cerebrospinal fluid beyond the foramen magnum and to stop the progression of a syringomyelia. Despite recent advances in imaging and surgery, even today, there is no consensus on optimal management of CM-I. Ongoing focus is devoted to a better consideration of the pathophysiology of CM-I and the development of more effective medical and surgical treatments. It is hoped that proposed algorithm helps the neurosurgeon to provide a precise management for patients with CM-I in advance.
I型Chiari畸形（CM-I）的诊断基于脑部或颈脊髓的磁共振成像。手术的主要目标是解除枕大孔水平以下脑脊液自由搏动性流动的梗阻，并阻止脊髓空洞症的进展。尽管近年来在影像学和手术方面取得了进展，但即便在今天，对于CM-I的最佳治疗仍未达成共识。目前的重点是更好地考虑CM-I的病理生理学，并开发更有效的药物和手术治疗方法。希望所提出的算法能帮助神经外科医生提前为CM-I患者提供精确的治疗方案。
