镍（II）催化芳烃与α,α'-二溴烯烃的串联C（sp）-H键活化和环化反应

Nickel(ii)-catalyzed tandem C(sp)-H bond activation and annulation of arenes with -dibromoalkenes.

作者信息

Shi Yun, Li Meng-Sheng, Zhang Fangdong, Chen Baohua

机构信息

State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province Lanzhou 730000 P. R. China

出版信息

RSC Adv. 2018 Aug 13;8(50):28668-28675. doi: 10.1039/c8ra03278e. eCollection 2018 Aug 7.

A nickel(ii)/silver(i)-catalyzed tandem C(sp)-H activation and intramolecular annulation of arenes with dibromoalkenes has been successfully achieved, which offers an efficient approach to the 3-methyleneisoindolin-1-one scaffold. Attractive features of this system include its low cost, ease of operation, and its ability to access a wide range of isoindolinones.