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钛制备富血小板纤维蛋白、EndoSequence根修复材料和氢氧化钙作为恒牙不可逆性牙髓炎活髓切断术药物的比较评估:一项随机对照试验。

Comparative assessment of titanium-prepared platelet-rich fibrin, EndoSequence root repair material, and calcium hydroxide as pulpotomy agents in permanent teeth with irreversible pulpitis: A randomized controlled trial.

作者信息

Doranala Suryasowjanya, Surakanti Jayaprada Reddy, Vemisetty Harikumar, Loka Suraj Reddy, Sudireddy Keerthi, Punna Rajani

机构信息

Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Hyderabad, Telangana, India.

Department of Conservative Dentistry and Endodontics, Kamineni Institute Dental Sciences, Hyderabad, Telangana, India.

出版信息

J Conserv Dent. 2021 Nov-Dec;24(6):606-610. doi: 10.4103/jcd.jcd_264_21. Epub 2022 Apr 1.

DOI:10.4103/jcd.jcd_264_21
PMID:35558675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9089767/
Abstract

CONTEXT

Pulpotomy is a procedure in which part of an exposed vital pulp is removed, usually as a means of preserving the vitality and function of the remaining part.

AIM

The aim is to compare the effectiveness of Dycal (CH), EndoSequence, and Titanium-prepared platelet-rich fibrin with EndoSequence (T-PRF) as pulpotomy agents in mature permanent molars with irreversible pulpitis.

SETTINGS AND DESIGN

Sixty permanent mandibular molars with carious exposure and symptoms of irreversible pulpitis were randomly allocated to three groups.

SUBJECTS AND METHODS

Full pulpotomy was performed using Dycal, EndoSequence, and T-PRF with EndoSequence as pulpotomy agents. Pain intensity was analyzed using a Numeric Rating Scale score at baseline 24 h, 7 days, 6 months, and 1 year. The clinical and radiographic evaluations were done at 6 months and 1 year.

STATISTICAL ANALYSIS

Nonparametric tests (Kruskal-Wallis, Chi-square) were applied to analyze the data as the normality test does not follow a normal distribution.

RESULTS

T-PRF and EndoSequence showed effective results when compared clinically, and there was no significant difference between radiographic success rates among the three groups at ( = 0.325 at 6 months, 0.466 at 12 months) follow-up.

CONCLUSION

T-PRF and EndoSequence showed higher success rates among Dycal, EndoSequence as pulpotomy agents in teeth with irreversible pulpitis.

摘要

背景

活髓切断术是一种切除部分暴露的牙髓的手术,通常作为保留剩余牙髓活力和功能的一种手段。

目的

比较Dycal(氢氧化钙)、EndoSequence以及含钛富血小板纤维蛋白联合EndoSequence(T-PRF)作为活髓切断术药物用于治疗患有不可逆性牙髓炎的成熟恒牙的有效性。

设置与设计

将60颗患有龋洞暴露且有不可逆性牙髓炎症状的下颌恒牙随机分为三组。

研究对象与方法

分别使用Dycal、EndoSequence以及T-PRF联合EndoSequence作为活髓切断术药物进行全髓切断术。使用数字评分量表在基线、24小时、7天、6个月和1年时分析疼痛强度。在6个月和1年时进行临床和影像学评估。

统计分析

由于正态性检验不服从正态分布,因此应用非参数检验(Kruskal-Wallis检验、卡方检验)来分析数据。

结果

在临床比较中,T-PRF和EndoSequence显示出有效的结果,在随访6个月(χ² = 0.325)和12个月(χ² = 0.466)时,三组之间的影像学成功率没有显著差异。

结论

在患有不可逆性牙髓炎的牙齿中,T-PRF和EndoSequence作为活髓切断术药物在Dycal、EndoSequence中显示出更高的成功率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c55/9089767/fac3d07c466d/JCD-24-606-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c55/9089767/30abf0514b78/JCD-24-606-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c55/9089767/e9953af434ad/JCD-24-606-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c55/9089767/fac3d07c466d/JCD-24-606-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c55/9089767/30abf0514b78/JCD-24-606-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c55/9089767/e9953af434ad/JCD-24-606-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c55/9089767/fac3d07c466d/JCD-24-606-g003.jpg

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2
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J Endod. 2017 Dec;43(12):1953-1962. doi: 10.1016/j.joen.2017.08.007. Epub 2017 Oct 20.
3
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4
Comparison of bioactive material failure rates in vital pulp treatment of permanent matured teeth - a systematic review and network meta-analysis.恒牙成熟牙髓治疗中生物活性材料失败率的比较——一项系统评价和网状荟萃分析
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5
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6
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7
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8
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9
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10
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Iran Endod J. 2013 Spring;8(2):65-8. Epub 2013 May 1.