Zhang Jian, Han Xu, Su Diansan, Gu Xiyao, Yu Weifeng
NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Jiangsu Province Key Laboratory of Anesthesiology, Jiangsu Province Key laboratory of Anesthesia and Analgesia, Xuzhou Medical University, Xuzhou, China.
Department of Anesthesiology, Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Front Med (Lausanne). 2022 Apr 26;9:850762. doi: 10.3389/fmed.2022.850762. eCollection 2022.
Herpes zoster infection, with its considerable burden to individuals and society, remains a challenge around the world. However, to the knowledge of the authors, little bibliometric quantitative or qualitative analysis has been carried out to evaluate herpes zoster research. This study aimed to use a bibliometric analysis to evaluate current publication trends and hotspots on herpes zoster research worldwide, in order to advance research in this field.
Relevant publications from January 2012 to December 2021 were collected from the Web of Science Core Collection database. Citespace (V5.8.R3) was used to analyze the research points, including publication countries, institutions and authors, cited author, cited reference and their clustering, and keyword co-occurrence, and burst keyword to acquire research trends and hotspots.
A total of 9,259 publications were obtained, with a steady increase in the number of annual publications during the decade. Articles were the main type of publication. The United States is the leading country in this research, and the University of Colorado has the highest influence in this field. Oxman is the most representative author, with a main research interest in herpes zoster vaccines. The top five cited authors' publications focused on herpes zoster vaccines, molecular mechanisms, and postherpetic neuralgia. A co-citation map resulted 19 main clusters, and revealed that vaccines, postherpetic neuralgia, treatments, varicella zoster virus and its mechanisms, and epidemiology of herpes zoster were the current research focus after clustering co-cited publications. Human herpesviruses, antiviral prophylaxis, rheumatoid arthritis, recombinant zoster vaccine, varicella vaccination and postherpetic neuralgia were the top clusters after co-occurrence keywords analysis. Moreover, burst keywords detection showed that the subunit vaccine was the new hotspot in the field of herpes zoster.
This bibliometric study defined the overall prospects in the field of herpes zoster and provided valuable instruction for the ongoing research. The keyword "subunit vaccine" indicated that a vaccine for herpes zoster prevention was the hotspot. Efforts to prevent varicella zoster virus infection will be essential to improve herpes zoster outcomes.
带状疱疹感染给个人和社会带来了相当大的负担，在全球范围内仍然是一项挑战。然而，据作者所知，很少有文献计量学的定量或定性分析来评估带状疱疹研究。本研究旨在通过文献计量分析来评估全球带状疱疹研究的当前出版趋势和热点，以推动该领域的研究。
从科学网核心合集数据库中收集2012年1月至2021年12月的相关出版物。使用Citespace（V5.8.R3）分析研究要点，包括出版国家、机构和作者、被引作者、被引参考文献及其聚类，以及关键词共现和突现关键词，以获取研究趋势和热点。
共获得9259篇出版物，十年间年出版物数量稳步增加。文章是主要的出版类型。美国是该研究的领先国家，科罗拉多大学在该领域影响力最大。奥克斯曼是最具代表性的作者，主要研究兴趣是带状疱疹疫苗。被引次数最多的前五位作者的出版物集中在带状疱疹疫苗、分子机制和带状疱疹后神经痛。共被引图谱产生了19个主要聚类，聚类共被引出版物后发现疫苗、带状疱疹后神经痛、治疗、水痘带状疱疹病毒及其机制以及带状疱疹流行病学是当前的研究重点。人类疱疹病毒、抗病毒预防、类风湿性关节炎、重组带状疱疹疫苗、水痘疫苗接种和带状疱疹后神经痛是共现关键词分析后的前几大聚类。此外，突现关键词检测表明亚单位疫苗是带状疱疹领域的新热点。
这项文献计量学研究明确了带状疱疹领域的总体前景，并为正在进行的研究提供了有价值的指导。关键词“亚单位疫苗”表明预防带状疱疹的疫苗是热点。预防水痘带状疱疹病毒感染的努力对于改善带状疱疹的治疗结果至关重要。
