Chan-Yeung M, Malo J L
Chest. 1987 Jun;91(6 Suppl):130S-136S. doi: 10.1378/chest.91.6_supplement.130s.
This article review recent developments in the study of occupational asthma and implications for the overall understanding of asthma. Occupational asthma is a clinical syndrome caused by many different agents. Contribution of studies of experimental inhalation challenge using occupational agents to the knowledge of asthmatic reactions and their mechanisms is discussed. Investigations in the occupational environment into predisposing factors and persistence or recovery after exposure to an allergic agent or nonspecific irritant are reviewed. Approaches to diagnosing asthma in the occupational environment and to assessing functional impairment and disability are outlined. Directions for future research are identified.
本文综述了职业性哮喘研究的最新进展及其对哮喘整体认识的意义。职业性哮喘是由多种不同因素引起的临床综合征。讨论了使用职业性因素进行实验性吸入激发研究对哮喘反应及其机制认识的贡献。综述了在职业环境中对易患因素以及接触过敏原或非特异性刺激物后的持续存在或恢复情况的调查。概述了在职业环境中诊断哮喘以及评估功能损害和残疾的方法。确定了未来研究的方向。
