Callen J P
Dis Mon. 1987 May;33(5):237-305. doi: 10.1016/0011-5029(87)90022-8.
Dermatomyositis and polymyositis are related disorders of unknown cause in which immunologic changes may be important. They sometimes overlap with other collagen vascular diseases, and not infrequently are associated with malignancy. The clinical features of the adult and juvenile forms of the disorder and the visceral manifestations of DM-PM are outlined, along with enzymatic, electromyographic, and histologic aids to diagnosis. While the cutaneous lesions often are resistant to treatment, systemic involvement may respond to corticosteroids or to immunosuppressive drugs. Treatment definitely alters the prognosis in cases not associated with malignancy.
皮肌炎和多发性肌炎是病因不明的相关疾病，其中免疫变化可能很重要。它们有时与其他胶原血管疾病重叠，且常与恶性肿瘤相关。本文概述了该疾病成人和青少年形式的临床特征以及皮肌炎 - 多发性肌炎的内脏表现，同时介绍了用于诊断的酶学、肌电图和组织学辅助手段。虽然皮肤病变通常对治疗有抵抗性，但全身受累情况可能对皮质类固醇或免疫抑制药物有反应。在与恶性肿瘤无关的病例中，治疗肯定会改变预后。
