Calysepins I-VII, Hexasaccharide Resin Glycosides from and Their Cytotoxic Evaluation.

Seven new hexasaccharide resin glycosides, named calysepins I-VII (-), with 27-membered rings, were obtained from the aerial parts of . Their structures with absolute configuration were established on the basis of spectroscopic data interpretation analysis and the use of chemical methods. They were defined as hexasaccharides composed of one d-quinovose, four d-glucose, and one l-rhamnose unit, and their sugar moieties were partially acylated by (2)methylbutanoic acid in - and (2,3)-nilic acid in - and , which mainly differed at the positions of acylation. Additionally, calysepin IV () exhibited cytotoxicity against A549 cells with an IC value of 5.2 μM.