School of Agriculture, Tokai University, 5435 Minamiaso, Aso, Kumamoto 869-1404, Japan.
J Nat Prod. 2011 Nov 28;74(11):2414-9. doi: 10.1021/np2006378. Epub 2011 Oct 12.
Four new resin glycosides having intramolecular cyclic ester structures (jalapins), named calysolins I-IV (1-4), were isolated from the methanol extract of leaves, stems, and roots of Calystegia soldanella , along with one known jalapin (5) derivative. The structures of 1-4 were determined on the basis of spectroscopic data and chemical evidence. They fall into two types, one having a 22-membered ring (1 and 4) and the other with a 27-membered ring (2 and 3). The sugar moieties of 1-4 were partially acylated by some organic acids. Compound 4 is the first example of a hexaglycoside of jalapin.
四种具有分子内环状酯结构的新树脂糖苷（育亨宾），命名为 calysolins I-IV（1-4），从喇叭藤的叶、茎和根的甲醇提取物中分离得到，此外还有一种已知的育亨宾衍生物（5）。基于光谱数据和化学证据确定了 1-4 的结构。它们分为两种类型，一种具有 22 元环（1 和 4），另一种具有 27 元环（2 和 3）。1-4 的糖部分被一些有机酸部分酰化。化合物 4 是育亨宾六糖苷的首例。
