Department of Pathology, Batman Training and Research Hospital, Batman, Turkey.
UCSF Department of Pathology, Neuropathology Division, San Francisco, CA, USA.
Indian J Pathol Microbiol. 2022 May;65(Supplement):S33-S41. doi: 10.4103/ijpm.ijpm_1019_21.
The newest revision of the WHO classification of tumors of the central nervous system, also known as WHO 5 edition, introduces substantial changes, especially within the glial tumor category and separates adult-type and pediatric-type glial tumors into different categories for the first time. In addition, another category of glial tumors, "Circumscribed Astrocytic Gliomas" were also created. This group includes pilocytic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, chordoid glioma, astroblastoma, and the highly nebulous novel entity high-grade astrocytoma with piloid features. We present a brief and critical review of the pathological and molecular characteristics of these often well-demarcated tumors that can occur in adults as well as in the pediatric population.
世界卫生组织（WHO）中枢神经系统肿瘤分类的最新修订版，也被称为 WHO 第 5 版，引入了实质性的变化，特别是在神经胶质肿瘤类别中，并首次将成人型和儿童型神经胶质肿瘤分为不同的类别。此外，还创建了另一个神经胶质肿瘤类别，即“局限性星形细胞瘤”。该组包括毛细胞型星形细胞瘤、多形性黄色星形细胞瘤、室管膜下巨细胞星形细胞瘤、脉络丛胶质瘤、星形母细胞瘤以及高度模糊的新型实体伴微囊形成的高级别星形细胞瘤。我们简要而批判性地回顾了这些通常边界清楚的肿瘤的病理和分子特征，这些肿瘤可发生于成人和儿童人群。
