Dykes A K, Christensen K K, Christensen P
Eur J Obstet Gynecol Reprod Biol. 1987 Apr;24(4):293-7. doi: 10.1016/0028-2243(87)90154-7.
The effect of vaginal washing with chlorhexidine acetate, 2 g/l at delivery, on the colonization of the urogenital tract with group B streptococci (GBS) 4 days later was investigated. Patients who were culture-positive for GBS in urethra and/or cervix in pregnancy weeks 32 and 36 as well as at delivery were included in a prospective study. The washing procedure was performed in 31 parturients, and 10 (32%) were culture-negative at day 4 after delivery. In contrast, only 7/47 (15%) non-washed controls were negative at day 4 (p = 0.044). The results demonstrate a prolonged suppressive effect of vaginal washing with chlorhexidine on the recovery of GBS from the urogenital tract in this highly selected patient group.
研究了在分娩时用2 g/l醋酸氯己定进行阴道冲洗对4天后B族链球菌（GBS）在泌尿生殖道定植的影响。在妊娠第32周、第36周以及分娩时尿道和/或宫颈GBS培养呈阳性的患者被纳入一项前瞻性研究。31名产妇进行了冲洗程序，其中10名（32%）在分娩后第4天培养为阴性。相比之下，47名未冲洗的对照组中只有7名（15%）在第4天为阴性（p = 0.044）。结果表明，在这个经过高度筛选的患者群体中，用氯己定进行阴道冲洗对泌尿生殖道GBS的恢复具有延长的抑制作用。
