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大鼠中从海马角到内侧前额叶皮质直接投射的解剖学和电生理学证据。

Anatomical and electrophysiological evidence for a direct projection from Ammon's horn to the medial prefrontal cortex in the rat.

作者信息

Ferino F, Thierry A M, Glowinski J

出版信息

Exp Brain Res. 1987;65(2):421-6. doi: 10.1007/BF00236315.

DOI:10.1007/BF00236315
PMID:3556468
Abstract

Following microinjection of wheat germ agglutinin-horseradish peroxidase (WGA-HRP) into the medial prefrontal cortex (defined as the neocortical area innervated by the thalamic mediodorsal nucleus) labelled cells were observed in the pyramidal layer of the CA1 field of Ammon's horn. Observations made using antidromic stimulation confirmed these results, and revealed that slow conduction velocity of the fibers of the hippocampal cells innervating the prefrontal cortex. Taken together, these data provide evidence for a direct projection of CA1 cells to the medial prefrontal cortex.

摘要

将小麦胚凝集素-辣根过氧化物酶(WGA-HRP)微量注射到内侧前额叶皮层(定义为由丘脑背内侧核支配的新皮层区域)后,在海马角CA1区的锥体细胞层观察到标记细胞。使用逆向刺激进行的观察证实了这些结果,并揭示了支配前额叶皮层的海马细胞纤维传导速度缓慢。综上所述,这些数据为CA1细胞向内侧前额叶皮层的直接投射提供了证据。

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